Respiratory Syncytial Virus–Induced Activation of Nuclear Factor–κB in the Lung Involves Alveolar Macrophages and Toll-Like Receptor 4–Dependent Pathways

The transcription factor nuclear factor (NF)–κB controls the expression of numerous respiratory syncytial virus (RSV)–inducible inflammatory and immunomodulatory genes. Using a BALB/c mouse model, the present article shows that RSV potently and specifically activates NF-κB in vivo, a process that in...

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Veröffentlicht in:	The Journal of infectious diseases 2002-11, Vol.186 (9), p.1199-1206
Hauptverfasser:	Haeberle, Helene A., Takizawa, Ryuta, Casola, Antonella, Brasier, Allan R., Dieterich, Hans-Juergen, van Rooijen, Nico, Gatalica, Zoran, Garofalo, Roberto P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial diseases Bacterial diseases of the respiratory system Biological and medical sciences Human bacterial diseases Infectious diseases Medical sciences Pneumology Respiratory system : syndromes and miscellaneous diseases
Online-Zugang:	Volltext
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