Pharmacogenetics-Based New Therapeutic Concepts

Pharmacogenetics, one of the fields of clinical pharmacology, studies how genetic factors influence drug response. If hereditary traits are taken into account appropriately before starting drug treatment, the type of drug and its dosage can be tailored to the individual patient's needs. Pharmac...

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Veröffentlicht in:	Drug metabolism reviews 2004, Vol.36 (3-4), p.617-638
Hauptverfasser:	Roots, Ivar, Gerloff, Thomas, Meisel, Christian, Kirchheiner, Julia, Goldammer, Mark, Kaiser, Rolf, Laschinski, Gabriele, Brockmöller, Jürgen, Cascorbi, Ingolf, Kleeberg, Ullrich, Hildebrandt, Alfred G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences CYP2C19 CYP2D6 Cytochrome P-450 Enzyme System - genetics Cytochrome P-450 Enzyme System - metabolism Drug transporters General pharmacology Genetic Variation - drug effects Genetic Variation - genetics Humans Individualized medicine Medical sciences Pharmaceutical Preparations - administration & dosage Pharmaceutical Preparations - metabolism Pharmacogenetics Pharmacogenetics - methods Pharmacogenetics - statistics & numerical data Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions Pharmacology. Drug treatments Polymorphism, Single Nucleotide - drug effects Polymorphism, Single Nucleotide - genetics Proton pump inhibitors Xenobiotics - metabolism
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