In Vitro Release Behavior of Toremifene Citrate from Sol-Gel Processed Sintered Silica Xerogels

Factors affecting the adsorption and desorption of toremifene citrate (TC) on sintered silica xerogels were investigated in vitro. TC was attached onto sol-gel processed sintered silica xerogel grains or disks by adsorption. The adsorption of TC on the surface of silica was pH dependent. The results...

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Veröffentlicht in:	Drug development and industrial pharmacy 1999-01, Vol.25 (8), p.955-959
Hauptverfasser:	Ahola, Manja, Kortesuo, Pirjo, Kangasniemi, Ilkka, Kiesvaara, Juha, Yli-Urpo, Antti
Format:	Artikel
Sprache:	eng
Schlagworte:	Adsorption Antineoplastic Agents, Hormonal - administration & dosage Biological and medical sciences Crystallization Drug Carriers Estrogen Antagonists - administration & dosage Gels General pharmacology Medical sciences Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Porosity Silicon Dioxide Solubility Spectrophotometry, Infrared Surface Properties Toremifene - administration & dosage
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