Poly(amido amine) dendrimers in oral delivery

Poly(amidoamine) (PAMAM) dendrimers have been extensively investigated for oral delivery applications due to their ability to translocate across the gastrointestinal epithelium. In this Review, we highlight recent advances in the evaluation of PAMAM dendrimers as oral drug delivery carriers. Specifi...

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Veröffentlicht in:	Tissue barriers 2016-04, Vol.4 (2), p.e1173773-e1173773
Hauptverfasser:	Yellepeddi, Venkata K., Ghandehari, Hamidreza
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals bioavailability Caco-2 monolayer complexation conjugation cytotoxicity Dendrimers - administration & dosage Dendrimers - adverse effects Dendrimers - chemistry Dendrimers - pharmacokinetics Humans Intestinal Absorption PAMAM dendrimers permeability Polyamines - chemistry Review translocation ussing chamber
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