Economic evaluation of adolescents and adults' pertussis vaccination: A systematic review of current strategies

The reemergence of pertussis in the last two decades led to the introduction of adolescents and adults immunization strategies of tetanus-diphtheria-acellular pertussis vaccines (Tdap) in several countries. The health authorities must consider economic aspects when deciding to recommend and fund new...

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Veröffentlicht in:Human vaccines & immunotherapeutics 2019-01, Vol.15 (1), p.14-27
Hauptverfasser: Fernandes, Eder Gatti, Rodrigues, Camila Cristina Martini, Sartori, Ana Marli Christovam, De Soárez, Patrícia Coelho, Novaes, Hillegonda Maria Dutilh
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container_issue 1
container_start_page 14
container_title Human vaccines & immunotherapeutics
container_volume 15
creator Fernandes, Eder Gatti
Rodrigues, Camila Cristina Martini
Sartori, Ana Marli Christovam
De Soárez, Patrícia Coelho
Novaes, Hillegonda Maria Dutilh
description The reemergence of pertussis in the last two decades led to the introduction of adolescents and adults immunization strategies of tetanus-diphtheria-acellular pertussis vaccines (Tdap) in several countries. The health authorities must consider economic aspects when deciding to recommend and fund new programs. Here we present a systematic review of worldwide full economic evaluations of pertussis vaccination targeting adolescents or adults published from 2000. Studies were identified by searching MEDLINE, Excerpta Medica, CRD, and Lilacs databases. Twenty-seven economic evaluations of different strategies with Tdap were identified. Booster vaccination for adolescents and adults were the most frequent, followed by cocooning and pregnant women vaccination. Strategies performance varied considerably among different studies. Assumptions regarding underreporting correction, herd protection and vaccine coverage were crucial to cost-effectiveness results. Understanding the model and the parameters used is essential to understand the results, and identify the major issues important to public health decisions.
doi_str_mv 10.1080/21645515.2018.1509646
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subjects Adolescent
Adult
Age Factors
Cost-Benefit Analysis
Diphtheria-Tetanus-acellular Pertussis Vaccines - administration & dosage
Diphtheria-Tetanus-acellular Pertussis Vaccines - economics
economic evaluation
Female
Humans
Immunization, Secondary
Maternal Health
maternal immunization
pertussis vaccination
Pregnancy
Review
systematic review
Vaccination - economics
Whooping Cough - prevention & control
title Economic evaluation of adolescents and adults' pertussis vaccination: A systematic review of current strategies
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