The expression profiles and regulation of PD-L1 in tumor-induced myeloid-derived suppressor cells

Programmed death-ligand 1 (PD-L1) is an inhibitory ligand that binds to PD-1 to suppress T cell activation. PD-L1 is constitutively expressed and inducible in tumor cells, but the expression profiles and regulatory mechanism of PD-L1 in myeloid-derived suppressor cells (MDSCs) are largely unknown. W...

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Veröffentlicht in:	Oncoimmunology 2016-12, Vol.5 (12), p.e1247135-e1247135
Hauptverfasser:	Lu, Chunwan, Redd, Priscilla S., Lee, Jeffrey R., Savage, Natasha, Liu, Kebin
Format:	Artikel
Sprache:	eng
Schlagworte:	IFNγ MDSCs MSI colon cancer MSS colon cancer Original Research PD-L1 T cells
Online-Zugang:	Volltext
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