Pathogenicity and virulence of Japanese encephalitis virus: Neuroinflammation and neuronal cell damage

Thousands of human deaths occur annually due to Japanese encephalitis (JE), caused by Japanese encephalitis virus. During the virus infection of the central nervous system, reactive gliosis, uncontrolled inflammatory response, and neuronal cell death are considered as the characteristic features of...

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Veröffentlicht in:	Virulence 2021-12, Vol.12 (1), p.968-980
Hauptverfasser:	Ashraf, Usama, Ding, Zhen, Deng, Shunzhou, Ye, Jing, Cao, Shengbo, Chen, Zheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Cell Death Encephalitis Virus, Japanese - pathogenicity Encephalitis, Japanese - complications Encephalitis, Japanese - virology Endoplasmic Reticulum Chaperone BiP glia Humans Inflammation - virology Japanese encephalitis Mice Nervous System Diseases - virology neuroinflammation neuronal cell damage Neurons - pathology Neurons - virology Proto-Oncogene Mas Review Signal Transduction therapy Virulence
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