The leucine biosynthetic pathway is crucial for adaptation to iron starvation and virulence in Aspergillus fumigatus

In contrast to mammalia, fungi are able to synthesize the branched-chain amino acid leucine de novo. Recently, the transcription factor LeuB has been shown to cross-regulate leucine biosynthesis, nitrogen metabolism and iron homeostasis in Aspergillus fumigatus, the most common human mold pathogen....

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Veröffentlicht in:	Virulence 2019-01, Vol.10 (1), p.925-934
Hauptverfasser:	Orasch, Thomas, Dietl, Anna-Maria, Shadkchan, Yana, Binder, Ulrike, Bauer, Ingo, Lass-Flörl, Cornelia, Osherov, Nir, Haas, Hubertus
Format:	Artikel
Sprache:	eng
Schlagworte:	amino acid biosynthesis Aspergillus fumigatus iron leucine Research Paper virulence
Online-Zugang:	Volltext
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