Nonreplicative functions of the origin recognition complex

Origin recognition complex (ORC), a heteromeric six-subunit complex, is the central component of the eukaryotic pre-replication complex. Recent data from yeast, frogs, flies and mammals present compelling evidence that ORC and its individual subunits have nonreplicative functions as well. The majori...

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Veröffentlicht in:Nucleus (Austin, Tex.) Tex.), 2018-01, Vol.9 (1), p.460-473
Hauptverfasser: Popova, Varvara V., Brechalov, Alexander V., Georgieva, Sofia G., Kopytova, Daria V.
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Sprache:eng
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