Bacteroides ovatus ATCC 8483 monotherapy is superior to traditional fecal transplant and multi-strain bacteriotherapy in a murine colitis model

Bacteriotherapy aimed at addressing dysbiosis may be therapeutic for Inflammatory Bowel Diseases (IBDs). We sought to determine if defined Bacteroides-based bacteriotherapy could be an effective and consistent alternative to fecal microbiota transplantation (FMT) in a murine model of IBD. We induced...

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Veröffentlicht in:	Gut microbes 2019-07, Vol.10 (4), p.504-520
Hauptverfasser:	Ihekweazu, Faith D., Fofanova, Tatiana Y., Queliza, Karen, Nagy-Szakal, Dorottya, Stewart, Christopher J., Engevik, Melinda A., Hulten, Kristina G., Tatevian, Nina, Graham, David Y., Versalovic, James, Petrosino, Joseph F., Kellermayer, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteria - classification Bacteria - growth & development bacteriotherapy Bacteroides Bacteroides - classification Bacteroides - growth & development Bacteroides - physiology Colitis - chemically induced Colitis - pathology Colitis - therapy Dextran Sulfate - toxicity Disease Models, Animal dysbiosis Fecal Microbiota Transplantation Feces - microbiology Gastrointestinal Tract - microbiology Gastrointestinal Tract - pathology Inflammation - prevention & control Inflammatory bowel disease Male Mice, Inbred C57BL microbiota Research Paper/Report RNA, Ribosomal, 16S - genetics Survival Analysis Treatment Outcome
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