CYRI/ Fam49 Proteins Represent a New Class of Rac1 Interactors

Fam49 proteins, now referred to as CYRI (CYFIP-related Rac Interactor), are evolutionarily conserved across many phyla. Their closest relative by amino acid sequence is CYFIP, as both proteins contain a domain of unknown function DUF1394. We recently showed that CYRI and the DUF1394 can mediate bind...

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Veröffentlicht in:	Communicative & integrative biology 2019-01, Vol.12 (1), p.112-118
Hauptverfasser:	Whitelaw, Jamie A., Lilla, Sergio, Paul, Nikki R., Fort, Loic, Zanivan, Sara, Machesky, Laura M.
Format:	Artikel
Sprache:	eng
Schlagworte:	actin cancer invasion cell migration GTPase signaling Rac1
Online-Zugang:	Volltext
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