Assessment of Tritium Behavior in Man Using a Modified Three-Compartment Model

In this study, on the basis of many human tritium metabolic data accumulated in the OKTAVIAN facility until now, the characteristics of the measured data have been analyzed for bioassay samples of urine, exhaled water and distilled water from urine. It has been found that the tritium concentration o...

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Veröffentlicht in:Journal of Nuclear Science and Technology 2002-04, Vol.39 (4), p.316-322
Hauptverfasser: YOSHIDA, Shigeo, MURATA, Isao, TAKAHASHI, Akito
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MURATA, Isao
TAKAHASHI, Akito
description In this study, on the basis of many human tritium metabolic data accumulated in the OKTAVIAN facility until now, the characteristics of the measured data have been analyzed for bioassay samples of urine, exhaled water and distilled water from urine. It has been found that the tritium concentration of exhaled water is equal to that in distilled water from urine. As a result, a new method has been developed to follow up each metabolism of two chemical forms, that is, free water tritium (FWT) and organically bound tritium (OBT) components in urine. In estimating the amount of retained tritium in the human body for a long time with their bioassay samples, it would vary depending upon the selection of samples. Moreover, a new tritium metabolic model has been developed by modifying a well-known, conventional three-compartment model, and verified with the measured data.
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source EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection; Free Full-Text Journals in Chemistry
subjects Applied sciences
bioassay sample
compartment model
Controled nuclear fusion plants
Energy
Energy. Thermal use of fuels
Exact sciences and technology
exhaled water
free water tritium
fusion reactors
Installations for energy generation and conversion: thermal and electrical energy
internal exposure
OKTAVIAN facility
organically bound tritium
tritium
urine
title Assessment of Tritium Behavior in Man Using a Modified Three-Compartment Model
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