An atom efficient, green synthesis of 2-pyrazoline derivatives under solvent-free conditions using grinding technique

A simple, rapid, efficient, and environmentally benign procedure for synthesis of 2-pyrazoline derivatives has been achieved by reacting 2′-hydroxychalcones with hydrazine hydrate under solvent-free grinding technique. The short reaction time, cleaner reaction, easy workup, higher yields, and mild r...

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Veröffentlicht in:	Green chemistry letters and reviews 2013-06, Vol.6 (2), p.123-127
Hauptverfasser:	Zangade, Sainath B., Mokle, Shyam S., Shinde, Avinash T., Vibhute, Yeshwant B.
Format:	Artikel
Sprache:	eng
Schlagworte:	2-pyrazolines 2′-hydroxychalcones Derivatives Green chemistry grinding technique solvent free
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description	A simple, rapid, efficient, and environmentally benign procedure for synthesis of 2-pyrazoline derivatives has been achieved by reacting 2′-hydroxychalcones with hydrazine hydrate under solvent-free grinding technique. The short reaction time, cleaner reaction, easy workup, higher yields, and mild reaction conditions make this protocol practical and economically attractive in comparison with the classical reaction.
doi_str_mv	10.1080/17518253.2012.713123
format	Article
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title	An atom efficient, green synthesis of 2-pyrazoline derivatives under solvent-free conditions using grinding technique
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