6-Hydroxydopamine induces secretion of PARK7/DJ-1 via autophagy-based unconventional secretory pathway

PARK7/DJ-1 is a Parkinson disease- and cancer-associated protein that functions as a multifunctional protein involved in gene transcription regulation and anti-oxidative defense. Although PARK7 lacks the secretory signal sequence, it is secreted and plays important physiological and pathophysiologic...

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Veröffentlicht in:	Autophagy 2018-11, Vol.14 (11), p.1943-1958
Hauptverfasser:	Urano, Yasuomi, Mori, Chinatsu, Fuji, Ayano, Konno, Keito, Yamamoto, Takayuki, Yashirogi, Shohei, Ando, Mayu, Saito, Yoshiro, Noguchi, Noriko
Format:	Artikel
Sprache:	eng
Schlagworte:	AMPK oxidative stress PARK7/DJ-1 parkinson disease Research Paper - Basic Science secretory autophagy unconventional secretion
Online-Zugang:	Volltext
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