Identification of circular RNAs hosted by the RPGR ORF15 genomic locus

Mutations in the retina-specific isoform of the gene encoding retinitis pigmentosa GTPase regulator (RPGR orf15 ) cause X-linked retinitis pigmentosa, a severe and early onset inherited retinal degeneration. The underlying pathogenic mechanisms and variability in disease severity remain to be fully...

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