Absence of the Fragile X Mental Retardation Protein results in defects of RNA editing of neuronal mRNAs in mouse

The fragile X syndrome (FXS), the most common form of inherited intellectual disability, is due to the absence of FMRP, a protein regulating RNA metabolism. Recently, an unexpected function of FMRP in modulating the activity of Adenosine Deaminase Acting on RNA (ADAR) enzymes has been reported both...

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Veröffentlicht in:RNA biology 2017-11, Vol.14 (11), p.1580-1591
Hauptverfasser: Filippini, Alice, Bonini, Daniela, Lacoux, Caroline, Pacini, Laura, Zingariello, Maria, Sancillo, Laura, Bosisio, Daniela, Salvi, Valentina, Mingardi, Jessica, La Via, Luca, Zalfa, Francesca, Bagni, Claudia, Barbon, Alessandro
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Sprache:eng
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