Upregulation of miR-128 Mediates Heart Injury by Activating Wnt/β-catenin Signaling Pathway in Heart Failure Mice

Cardiac hypertrophy contributes to heart failure and is pathogenically modulated by a network of signaling cascades including Wnt/β-catenin signaling pathway. miRNAs have been widely demonstrated to regulate gene expression in heart development. miR-128 was routinely found as a brain-enriched gene a...

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Veröffentlicht in:	Organogenesis 2021-10, Vol.17 (3-4), p.27-39
Hauptverfasser:	Li, Jing-Yao, Li, Xin-Chang, Tang, Yu-Long
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axin1 cardiac hypertrophy heart failure Heart Failure - metabolism Heart Failure - pathology Heart Injuries Humans Mice MicroRNAs - metabolism miR-128 Up-Regulation Wnt Signaling Pathway - physiology Wnt/β-catenin
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