Knockdown of RREB1 inhibits cell proliferation via enhanced p16 expression in gastric cancer

Gastric cancer (GC) is the most common gastrointestinal malignancy worldwide. However, the molecular mechanisms of the progression of GC are not fully understood. Ras-responsive element binding protein 1 (RREB1) is an oncogene in many types of cancer that is involved in various biological processes,...

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Veröffentlicht in:	Cell cycle (Georgetown, Tex.) Tex.), 2021-12, Vol.20 (23), p.2465-2475
Hauptverfasser:	Gao, Qi, Wu, Yunhua, Lu, Chaoxiang, Kai, Wang, Xie, Weike, Wang, Qi, Wang, Lei, Liu, Shiqi, Pan, Yongkang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - genetics Cell Line, Tumor cell proliferation Cell Proliferation - genetics Cyclin-Dependent Kinase Inhibitor p16 - biosynthesis Cyclin-Dependent Kinase Inhibitor p16 - genetics DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Gastric cancer Gene Knockdown Techniques Heterografts Humans Mice Mice, Nude Oncogenes Research Paper RREB1 Stomach Neoplasms - genetics Stomach Neoplasms - metabolism Stomach Neoplasms - pathology Transcription Factors
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