CXCL6 regulates cell permeability, proliferation, and apoptosis after ischemia-reperfusion injury by modulating Sirt3 expression via AKT/FOXO3a activation

Chemokine (C-X-C motif) ligand 6 (CXCL6), a member of the CXC chemokine family, reportedly mediates several processes such as inflammation, immunoreaction, cell growth, and metastasis through interaction with the chemokine receptors CXCR1 and CXCR2 in humans; further, CXCR1 and CXCR2 can promote rep...

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Veröffentlicht in:	Cancer biology & therapy 2021-01, Vol.22 (1), p.30-39
Hauptverfasser:	Wang, Xiaolin, Dai, Yuanqiang, Zhang, Xiaoxiu, Pan, Ke, Deng, Yu, Wang, Jiafeng, Xu, Tao
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT/FOXO3a pathway CXCL6/CXCR2 HIF-1α Ischemia-reperfusion injury Research Paper Sirt3
Online-Zugang:	Volltext
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