Emerging roles of circRNA_NEK6 targeting miR-370-3p in the proliferation and invasion of thyroid cancer via Wnt signaling pathway

Objective: To identify the significantly altered circRNAs and mRNAs in thyroid cancer, investigate their target miRNAs and determine their biological functions. Methods: The differentially expressed circRNAs, mRNAs and pathways in thyroid cancer were identified by microarray analysis and gene set en...

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Veröffentlicht in:	Cancer biology & therapy 2018-12, Vol.19 (12), p.1139-1152
Hauptverfasser:	Chen, Fukun, Feng, Zhiping, Zhu, Jialun, Liu, Pengjie, Yang, Chuanzhou, Huang, Rongkai, Deng, Zhiyong
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Cell Survival - genetics circRNA FZD8 Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene Regulatory Networks GSEA Humans KEGG MicroRNAs - genetics miR-370-3p Models, Biological NIMA-Related Kinases - genetics Research Paper RNA - genetics RNA Interference RNA, Circular thyroid cancer Thyroid Neoplasms - genetics Thyroid Neoplasms - metabolism Thyroid Neoplasms - pathology Wnt Signaling Pathway
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