Synthesis and evaluation of in vitro antiviral activity of 2-[3-(substituted phenyl)-4,5-dihydro-1H-5-pyrazolyl]benzofuran-3-yl chloride derivatives

3-Chlorobenzofuran-2-carbaldehyde was condensed with substituted acetophenone by using the Claisen-Schmidt condensation to obtain 3-(3-chlorobenzofuran-2-yl)-1-(substituted phenyl)-2-propen-1-one (2a-m) which upon further treatment with hydrazine hydrate gave 2-[3-(substituted phenyl)-4,5-dihydro-1H...

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Veröffentlicht in:Journal of enzyme inhibition and medicinal chemistry 2009-08, Vol.24 (4), p.949-956
Hauptverfasser: Shahar Yar, M., Mustaqeem Abdullah, M., Husain, A., Bhakht, M. Afroz, De Clercq, Erik
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Sprache:eng
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