Atrioventricular nodal ablation in patients with resynchronization therapy and atrial fibrillation - long term results
Objectives. Atrioventricular nodal ablation (AVNA) is recommended for patients (pts) with cardiac resynchronization therapy (CRT) having atrial fibrillation (AF) and incomplete ventricular capture (Class IIa, level B). AVNA reduces mortality and improves the New York Heart Association (NYHA) functio...
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Veröffentlicht in: | Scandinavian cardiovascular journal : SCJ 2017-06, Vol.51 (3), p.138-142 |
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description | Objectives. Atrioventricular nodal ablation (AVNA) is recommended for patients (pts) with cardiac resynchronization therapy (CRT) having atrial fibrillation (AF) and incomplete ventricular capture (Class IIa, level B). AVNA reduces mortality and improves the New York Heart Association (NYHA) functional class during intermediate term follow-up. The objectives were to study the long-term outcome regarding quality of life (QoL) and survival of our CRT pts after AVNA. Design. 37 CRT-pts undergoing AVNA due to inadequate biventricular pacing were included in the study. Data were retrospectively obtained from clinical records and through telephone interviews. Results. Twenty pts died during the follow-up period of average 30.6 ± 24 months. After AVNA the ventricular capture improved significantly from 68.4 ± 23% to 98.5 ± 2% (p |
doi_str_mv | 10.1080/14017431.2017.1307443 |
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Atrioventricular nodal ablation (AVNA) is recommended for patients (pts) with cardiac resynchronization therapy (CRT) having atrial fibrillation (AF) and incomplete ventricular capture (Class IIa, level B). AVNA reduces mortality and improves the New York Heart Association (NYHA) functional class during intermediate term follow-up. The objectives were to study the long-term outcome regarding quality of life (QoL) and survival of our CRT pts after AVNA. Design. 37 CRT-pts undergoing AVNA due to inadequate biventricular pacing were included in the study. Data were retrospectively obtained from clinical records and through telephone interviews. Results. Twenty pts died during the follow-up period of average 30.6 ± 24 months. After AVNA the ventricular capture improved significantly from 68.4 ± 23% to 98.5 ± 2% (p < 0.001). A significant and sustained improvement of average 0.3 ± 0.5 (p = 0.001) in NYHA functional class was found. Additionally a large percentage of pts discontinued taking rate reducing drugs with potential severe side effects. Conclusion. AVNA in CRT pts was safe and effective. The treatment resulted in a sustained improvement in QoL, including long-term improvement in NYHA functional class.</description><identifier>ISSN: 1401-7431</identifier><identifier>EISSN: 1651-2006</identifier><identifier>DOI: 10.1080/14017431.2017.1307443</identifier><identifier>PMID: 28345365</identifier><language>eng</language><publisher>England: Taylor & Francis</publisher><subject>Aged ; Atrial Fibrillation ; Atrial Fibrillation - diagnosis ; Atrial Fibrillation - mortality ; Atrial Fibrillation - physiopathology ; Atrial Fibrillation - surgery ; Atrioventricular Node - physiopathology ; Atrioventricular Node - surgery ; AV nodal ablation ; Cardiac Resynchronization Therapy - adverse effects ; Cardiac Resynchronization Therapy - mortality ; Catheter Ablation - adverse effects ; Catheter Ablation - methods ; Catheter Ablation - mortality ; Chronic Heart Failure ; Female ; Heart Failure - diagnosis ; Heart Failure - mortality ; Heart Failure - physiopathology ; Heart Failure - therapy ; Humans ; Interviews as Topic ; Male ; Medical Records ; Middle Aged ; Norway ; Quality of Life ; Recovery of Function ; Resynchronization therapy ; Retrospective Studies ; Risk Factors ; Survival Analysis ; Time Factors ; Treatment Outcome</subject><ispartof>Scandinavian cardiovascular journal : SCJ, 2017-06, Vol.51 (3), p.138-142</ispartof><rights>2017 Informa UK Limited, trading as Taylor & Francis Group 2017</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c366t-48a7b4754aaa09d796309acb151b0ef9efd57d3a501db0d364d2f3964a13df6a3</citedby><cites>FETCH-LOGICAL-c366t-48a7b4754aaa09d796309acb151b0ef9efd57d3a501db0d364d2f3964a13df6a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28345365$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aune, Arleen</creatorcontrib><creatorcontrib>Færestrand, Svein</creatorcontrib><creatorcontrib>Hoff, Per Ivar</creatorcontrib><creatorcontrib>Schuster, Peter</creatorcontrib><title>Atrioventricular nodal ablation in patients with resynchronization therapy and atrial fibrillation - long term results</title><title>Scandinavian cardiovascular journal : SCJ</title><addtitle>Scand Cardiovasc J</addtitle><description>Objectives. Atrioventricular nodal ablation (AVNA) is recommended for patients (pts) with cardiac resynchronization therapy (CRT) having atrial fibrillation (AF) and incomplete ventricular capture (Class IIa, level B). AVNA reduces mortality and improves the New York Heart Association (NYHA) functional class during intermediate term follow-up. The objectives were to study the long-term outcome regarding quality of life (QoL) and survival of our CRT pts after AVNA. Design. 37 CRT-pts undergoing AVNA due to inadequate biventricular pacing were included in the study. Data were retrospectively obtained from clinical records and through telephone interviews. Results. Twenty pts died during the follow-up period of average 30.6 ± 24 months. After AVNA the ventricular capture improved significantly from 68.4 ± 23% to 98.5 ± 2% (p < 0.001). A significant and sustained improvement of average 0.3 ± 0.5 (p = 0.001) in NYHA functional class was found. Additionally a large percentage of pts discontinued taking rate reducing drugs with potential severe side effects. Conclusion. AVNA in CRT pts was safe and effective. The treatment resulted in a sustained improvement in QoL, including long-term improvement in NYHA functional class.</description><subject>Aged</subject><subject>Atrial Fibrillation</subject><subject>Atrial Fibrillation - diagnosis</subject><subject>Atrial Fibrillation - mortality</subject><subject>Atrial Fibrillation - physiopathology</subject><subject>Atrial Fibrillation - surgery</subject><subject>Atrioventricular Node - physiopathology</subject><subject>Atrioventricular Node - surgery</subject><subject>AV nodal ablation</subject><subject>Cardiac Resynchronization Therapy - adverse effects</subject><subject>Cardiac Resynchronization Therapy - mortality</subject><subject>Catheter Ablation - adverse effects</subject><subject>Catheter Ablation - methods</subject><subject>Catheter Ablation - mortality</subject><subject>Chronic Heart Failure</subject><subject>Female</subject><subject>Heart Failure - diagnosis</subject><subject>Heart Failure - mortality</subject><subject>Heart Failure - physiopathology</subject><subject>Heart Failure - therapy</subject><subject>Humans</subject><subject>Interviews as Topic</subject><subject>Male</subject><subject>Medical Records</subject><subject>Middle Aged</subject><subject>Norway</subject><subject>Quality of Life</subject><subject>Recovery of Function</subject><subject>Resynchronization therapy</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Survival Analysis</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><issn>1401-7431</issn><issn>1651-2006</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtvFDEQhC0EIg_4CSAfucziXj9m5kYUBYgUiQucrZ6xzRp57MX2JFp-PV7thiOnqsNX1a0i5B2wDbCBfQTBoBccNtumG-CsF4K_IJegJHRbxtTL5hvTHaELclXKL8ZADhJek4vtwIXkSl6Sx5uafXq0scm8Bsw0JoOB4hSw-hSpj3TfXAMKffJ1R7Mthzjvcor-zwmpO5txf6AYDcXW0-LOT9mHc0VHQ4o_abV5OabXUMsb8sphKPbtWa_Jj89332-_dg_fvtzf3jx0M1eqdmLAfhK9FIjIRtOPirMR5wkkTMy60Toje8NRMjATM1wJs3V8VAKBG6eQX5MPp959Tr9XW6pefJlt-yzatBYNwwBCjIzxhsoTOudUSrZO77NfMB80MH2cXD9Pro-T6_PkLff-fGKdFmv-pZ43bsCnE-CjS3nBp5SD0RUPIWWXMc6-aP7_G38BRNeS7g</recordid><startdate>20170601</startdate><enddate>20170601</enddate><creator>Aune, Arleen</creator><creator>Færestrand, Svein</creator><creator>Hoff, Per Ivar</creator><creator>Schuster, Peter</creator><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20170601</creationdate><title>Atrioventricular nodal ablation in patients with resynchronization therapy and atrial fibrillation - long term results</title><author>Aune, Arleen ; Færestrand, Svein ; Hoff, Per Ivar ; Schuster, Peter</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c366t-48a7b4754aaa09d796309acb151b0ef9efd57d3a501db0d364d2f3964a13df6a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Aged</topic><topic>Atrial Fibrillation</topic><topic>Atrial Fibrillation - diagnosis</topic><topic>Atrial Fibrillation - mortality</topic><topic>Atrial Fibrillation - physiopathology</topic><topic>Atrial Fibrillation - surgery</topic><topic>Atrioventricular Node - physiopathology</topic><topic>Atrioventricular Node - surgery</topic><topic>AV nodal ablation</topic><topic>Cardiac Resynchronization Therapy - adverse effects</topic><topic>Cardiac Resynchronization Therapy - mortality</topic><topic>Catheter Ablation - adverse effects</topic><topic>Catheter Ablation - methods</topic><topic>Catheter Ablation - mortality</topic><topic>Chronic Heart Failure</topic><topic>Female</topic><topic>Heart Failure - diagnosis</topic><topic>Heart Failure - mortality</topic><topic>Heart Failure - physiopathology</topic><topic>Heart Failure - therapy</topic><topic>Humans</topic><topic>Interviews as Topic</topic><topic>Male</topic><topic>Medical Records</topic><topic>Middle Aged</topic><topic>Norway</topic><topic>Quality of Life</topic><topic>Recovery of Function</topic><topic>Resynchronization therapy</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Survival Analysis</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aune, Arleen</creatorcontrib><creatorcontrib>Færestrand, Svein</creatorcontrib><creatorcontrib>Hoff, Per Ivar</creatorcontrib><creatorcontrib>Schuster, Peter</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Scandinavian cardiovascular journal : SCJ</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aune, Arleen</au><au>Færestrand, Svein</au><au>Hoff, Per Ivar</au><au>Schuster, Peter</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Atrioventricular nodal ablation in patients with resynchronization therapy and atrial fibrillation - long term results</atitle><jtitle>Scandinavian cardiovascular journal : SCJ</jtitle><addtitle>Scand Cardiovasc J</addtitle><date>2017-06-01</date><risdate>2017</risdate><volume>51</volume><issue>3</issue><spage>138</spage><epage>142</epage><pages>138-142</pages><issn>1401-7431</issn><eissn>1651-2006</eissn><abstract>Objectives. Atrioventricular nodal ablation (AVNA) is recommended for patients (pts) with cardiac resynchronization therapy (CRT) having atrial fibrillation (AF) and incomplete ventricular capture (Class IIa, level B). AVNA reduces mortality and improves the New York Heart Association (NYHA) functional class during intermediate term follow-up. The objectives were to study the long-term outcome regarding quality of life (QoL) and survival of our CRT pts after AVNA. Design. 37 CRT-pts undergoing AVNA due to inadequate biventricular pacing were included in the study. Data were retrospectively obtained from clinical records and through telephone interviews. Results. Twenty pts died during the follow-up period of average 30.6 ± 24 months. After AVNA the ventricular capture improved significantly from 68.4 ± 23% to 98.5 ± 2% (p < 0.001). A significant and sustained improvement of average 0.3 ± 0.5 (p = 0.001) in NYHA functional class was found. Additionally a large percentage of pts discontinued taking rate reducing drugs with potential severe side effects. Conclusion. AVNA in CRT pts was safe and effective. The treatment resulted in a sustained improvement in QoL, including long-term improvement in NYHA functional class.</abstract><cop>England</cop><pub>Taylor & Francis</pub><pmid>28345365</pmid><doi>10.1080/14017431.2017.1307443</doi><tpages>5</tpages></addata></record> |
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subjects | Aged Atrial Fibrillation Atrial Fibrillation - diagnosis Atrial Fibrillation - mortality Atrial Fibrillation - physiopathology Atrial Fibrillation - surgery Atrioventricular Node - physiopathology Atrioventricular Node - surgery AV nodal ablation Cardiac Resynchronization Therapy - adverse effects Cardiac Resynchronization Therapy - mortality Catheter Ablation - adverse effects Catheter Ablation - methods Catheter Ablation - mortality Chronic Heart Failure Female Heart Failure - diagnosis Heart Failure - mortality Heart Failure - physiopathology Heart Failure - therapy Humans Interviews as Topic Male Medical Records Middle Aged Norway Quality of Life Recovery of Function Resynchronization therapy Retrospective Studies Risk Factors Survival Analysis Time Factors Treatment Outcome |
title | Atrioventricular nodal ablation in patients with resynchronization therapy and atrial fibrillation - long term results |
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