Beneficial effect of Amorphophallus paeoniifolius tuber on experimental ulcerative colitis in rats

Context: The tuber of Amorphophallus paeoniifolius (Dennst.) Nicolson (Araceae), commonly called Suran or Jimmikand, has high medicinal value and is used ethnomedicinally for the treatment of different gastrointestinal and inflammatory disorders. Objective: The present study evaluated the effects of...

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Veröffentlicht in:	Pharmaceutical biology 2017-01, Vol.55 (1), p.53-62
Hauptverfasser:	Dey, Yadu Nandan, Sharma, Garima, Wanjari, Manish M., Kumar, Dharmendra, Lomash, Vinay, Jadhav, Ankush D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic Acid Alkaline phosphatase Alkaline Phosphatase - blood Amorphophallus - chemistry Amorphophallus paeoniifolius Animals anti-inflammatory Anti-Inflammatory Agents - isolation & purification Anti-Inflammatory Agents - pharmacology Anti-Inflammatory Agents - toxicity antioxidant antioxidant activity Antioxidants Betulinic acid Biomarkers - blood blood serum Body weight Catalase Catalase - metabolism Colitis, Ulcerative - blood Colitis, Ulcerative - chemically induced Colitis, Ulcerative - pathology Colitis, Ulcerative - prevention & control Colon Colon - drug effects Colon - metabolism Colon - pathology Cytokines Cytokines - metabolism Cytoprotection Disease Models, Animal feces Gastrointestinal Agents - isolation & purification Gastrointestinal Agents - pharmacology Gastrointestinal Agents - toxicity glucomannans Glutathione Glutathione - metabolism histology histopathology inflammation Inflammation Mediators - metabolism Inflammatory bowel disease Inflammatory bowel diseases L-Lactate dehydrogenase L-Lactate Dehydrogenase - blood lactate dehydrogenase Lactic acid Length-weight relationships Lipid peroxidation Lipid Peroxidation - drug effects Male methanol myeloperoxidase Oral administration Oxidative Stress - drug effects Peroxidase Peroxidase - metabolism phytochemicals Phytotherapy Plant Extracts - isolation & purification Plant Extracts - pharmacology Plant Extracts - toxicity Plant Tubers Plants, Medicinal Prednisolone Prednisolone - pharmacology Rats, Wistar Solvents - chemistry Superoxide dismutase Superoxide Dismutase - metabolism Suran Tubers Ulcerative colitis
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