The pharmacology of psilocybin

Psilocybin (4‐phosphoryloxy‐N,N‐dimethyltryptamine) is the major psychoactive alkaloid of some species of mushrooms distributed worldwide.These mushrooms represent a growing problem regarding hallucinogenic drug abuse. Despite its experimental medical use in the 1960s, only very few pharmacological...

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Veröffentlicht in:	Addiction biology 2002-10, Vol.7 (4), p.357-364
Hauptverfasser:	Passie, Torsten, Seifert, Juergen, Schneider, Udo, Emrich, Hinderk M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Agaricales - chemistry Animals Brain - metabolism Controlled Clinical Trials as Topic Hallucinogens - adverse effects Hallucinogens - analysis Hallucinogens - pharmacokinetics Humans Mice Psilocybin - adverse effects Psilocybin - analysis Psilocybin - pharmacokinetics Receptors, Presynaptic - metabolism Serotonin - metabolism Somatoform Disorders - chemically induced Somatoform Disorders - classification Substance-Related Disorders
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Beschreibung
Zusammenfassung:	Psilocybin (4‐phosphoryloxy‐N,N‐dimethyltryptamine) is the major psychoactive alkaloid of some species of mushrooms distributed worldwide.These mushrooms represent a growing problem regarding hallucinogenic drug abuse. Despite its experimental medical use in the 1960s, only very few pharmacological data about psilocybin were known until recently. Because of its still growing capacity for abuse and the widely dispersed data this review presents all the available pharmacological data about psilocybin.
ISSN:	1355-6215 1369-1600
DOI:	10.1080/1355621021000005937