Improving the topical ocular pharmacokinetics of lyophilized cyclosporine A-loaded micelles: formulation, in vitro and in vivo studies

Dry eye syndrome (DES) is one of the most common disorders of the eye for which combined treatment includes modification of the ocular environment and pathogenic therapies. Cyclosporine A (CsA), a immunosuppressive agent, has been demonstrated to be effective for the treatment of DES but is limited...

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Veröffentlicht in:Drug delivery 2018, Vol.25 (1), p.888-899
Hauptverfasser: Yu, Yinglan, Chen, Daquan, Li, Yanan, Yang, Wenqian, Tu, Jiasheng, Shen, Yan
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Sprache:eng
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