Use of Natural Gums and Cellulose Derivatives in Production of Sustained Release Metoprolol Tablets

Metoprolol tartrate sustained-release tablets (100 mg) were prepared using xanthan/guar gums and also hydroxypropyl methyl cellulose (HPMC) carboxymethyl-Cellulose (CMC) polymers by direct compression method. Physical characteristics of the tablets and water uptake in addition to their dissolution p...

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Veröffentlicht in:	Drug delivery 2006-03, Vol.13 (2), p.113-119
Hauptverfasser:	Varshosaz, Jaleh, Tavakoli, Nasser, Eram, S. Ali
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Antagonists - chemistry Adrenergic beta-Antagonists - economics Adrenergic beta-Antagonists - pharmacokinetics Carboxymethyl-Cellulose Carboxymethylcellulose Sodium - analogs & derivatives Carboxymethylcellulose Sodium - chemistry Delayed-Action Preparations - chemistry Delayed-Action Preparations - economics Delayed-Action Preparations - pharmacokinetics Galactans - chemistry Guar Hydroxypropylmethyl-Cellulose Mannans - chemistry Metoprolol - chemistry Metoprolol - economics Metoprolol - pharmacokinetics Metoprolol Tartrate Oxazines Plant Gums Polysaccharides - chemistry Polysaccharides, Bacterial - chemistry Regression Analysis Sustained Release Tablets Tablets Technology, Pharmaceutical - methods Xanthan
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