Treatment-related myelodysplastic syndrome/acute myeloid leukemia in survivors of childhood cancer - An update
Treatment-related myelodysplastic syndrome/acute myeloid leukemia (t-MDS/t-AML) is a devastating complication of treatment for childhood cancer. However, the major cause of premature death of children treated for cancer remains their primary cancer. The understanding of the presentation, incidence,...
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| Veröffentlicht in: | Leukemia & lymphoma 2005-05, Vol.46 (5), p.651-663 |
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| container_title | Leukemia & lymphoma |
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| creator | Barnard, DR Woods, WG |
| description | Treatment-related myelodysplastic syndrome/acute myeloid leukemia (t-MDS/t-AML) is a devastating complication of treatment for childhood cancer. However, the major cause of premature death of children treated for cancer remains their primary cancer. The understanding of the presentation, incidence, predisposing risk factors and pathobiology of t-MDS/t-AML is increasing. This increased understanding has not yet been translated into improved outcomes of therapy for t-MDS/t-AML. However, newer approaches are under study. |
| doi_str_mv | 10.1080/10428190500051042 |
| format | Article |
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However, newer approaches are under study.</description><subject>Acute Disease</subject><subject>Antineoplastic Agents - adverse effects</subject><subject>Antineoplastic Combined Chemotherapy Protocols - adverse effects</subject><subject>Child</subject><subject>Female</subject><subject>Humans</subject><subject>Leukemia, Myeloid - chemically induced</subject><subject>Leukemia, Myeloid - etiology</subject><subject>Male</subject><subject>Myelodysplastic Syndromes - chemically induced</subject><subject>Myelodysplastic Syndromes - etiology</subject><subject>Neoplasms - therapy</subject><subject>Neoplasms, Second Primary - chemically induced</subject><subject>Neoplasms, Second Primary - etiology</subject><subject>Neoplasms, Second Primary - genetics</subject><subject>pediatric</subject><subject>Survivors</subject><subject>treatment-related acute myeloid leukemia</subject><subject>Treatment-related myelodysplastic syndrome</subject><issn>1042-8194</issn><issn>1029-2403</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UF1LwzAUDaI4nf4AXyR_oC5J065FX8bwCwa-zOdym6Q0M01G0k76723pQETY072X88E9B6E7Sh4oyciCEs4ympOEEJKMxxm6ooTlEeMkPh93zqKBwGfoOoTdyMpTdolmNCU0Twi7QnbrFbSNsm3klYFWSdz0yjjZh72B0GqBQ2-ld41agOhaNcFaYqO6L9VowNri0PmDPjgfsKuwqLWRtXMSC7BCeRzhlcXdXg7uN-iiAhPU7XHO0efL83b9Fm0-Xt_Xq00kOOFtlAugTKYVVTwpJWE0ySqWghAS0jSljAxQsiwpsIpTkcWQMr6Ml9mQULC8hHiO6OQrvAvBq6rYe92A7wtKirG74l93g-Z-0uy7slHyV3EsayA8TQRtK-cb-HbeyKKF3jhf-SGrDkV8yv_xj7xWYNpagFfFznXeDn2c-O4HXquQAA</recordid><startdate>20050501</startdate><enddate>20050501</enddate><creator>Barnard, DR</creator><creator>Woods, WG</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20050501</creationdate><title>Treatment-related myelodysplastic syndrome/acute myeloid leukemia in survivors of childhood cancer - An update</title><author>Barnard, DR ; Woods, WG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c404t-9ca12d6f1e45bd02158f26accda6661206f157b1a2f41c83a6247378000c29ba3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Acute Disease</topic><topic>Antineoplastic Agents - adverse effects</topic><topic>Antineoplastic Combined Chemotherapy Protocols - adverse effects</topic><topic>Child</topic><topic>Female</topic><topic>Humans</topic><topic>Leukemia, Myeloid - chemically induced</topic><topic>Leukemia, Myeloid - etiology</topic><topic>Male</topic><topic>Myelodysplastic Syndromes - chemically induced</topic><topic>Myelodysplastic Syndromes - etiology</topic><topic>Neoplasms - therapy</topic><topic>Neoplasms, Second Primary - chemically induced</topic><topic>Neoplasms, Second Primary - etiology</topic><topic>Neoplasms, Second Primary - genetics</topic><topic>pediatric</topic><topic>Survivors</topic><topic>treatment-related acute myeloid leukemia</topic><topic>Treatment-related myelodysplastic syndrome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Barnard, DR</creatorcontrib><creatorcontrib>Woods, WG</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Leukemia & lymphoma</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Barnard, DR</au><au>Woods, WG</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Treatment-related myelodysplastic syndrome/acute myeloid leukemia in survivors of childhood cancer - An update</atitle><jtitle>Leukemia & lymphoma</jtitle><addtitle>Leuk Lymphoma</addtitle><date>2005-05-01</date><risdate>2005</risdate><volume>46</volume><issue>5</issue><spage>651</spage><epage>663</epage><pages>651-663</pages><issn>1042-8194</issn><eissn>1029-2403</eissn><abstract>Treatment-related myelodysplastic syndrome/acute myeloid leukemia (t-MDS/t-AML) is a devastating complication of treatment for childhood cancer. 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| fulltext | fulltext |
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| ispartof | Leukemia & lymphoma, 2005-05, Vol.46 (5), p.651-663 |
| issn | 1042-8194 1029-2403 |
| language | eng |
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| source | MEDLINE; Taylor & Francis:Master (3349 titles); Taylor & Francis Medical Library - CRKN |
| subjects | Acute Disease Antineoplastic Agents - adverse effects Antineoplastic Combined Chemotherapy Protocols - adverse effects Child Female Humans Leukemia, Myeloid - chemically induced Leukemia, Myeloid - etiology Male Myelodysplastic Syndromes - chemically induced Myelodysplastic Syndromes - etiology Neoplasms - therapy Neoplasms, Second Primary - chemically induced Neoplasms, Second Primary - etiology Neoplasms, Second Primary - genetics pediatric Survivors treatment-related acute myeloid leukemia Treatment-related myelodysplastic syndrome |
| title | Treatment-related myelodysplastic syndrome/acute myeloid leukemia in survivors of childhood cancer - An update |
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