Usefulness of RA and RO Isoforms of Common Leukocyte Antigen (CD45) for Early Distinction Between Normal and Abnormal Promyelocytes

Normal promyelocytes express CD45RO, while acute promyelocytic leukemia (APL) blasts express CD45RA, both isoforms of common leukocyte antigen with mutually exclusive expression. Here we report a patient with accumulation of promyelocytes in the bone marrow and the diagnostic strategy is described a...

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Veröffentlicht in:	Leukemia & lymphoma 2002, Vol.43 (9), p.1823-1825
Hauptverfasser:	D'Arena, Giovanni, Cascavilla, Nicola, Nunziata, Giuseppe, Perla, Gianni, Matera, Rosella, Carella, Angelo Michele, Pistolese, Giuseppe
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone Marrow Cells - metabolism Cd45ra Cd45ro Female Flow Cytometry Granulocyte Precursor Cells - metabolism Humans Immunophenotyping Leukemia, Promyelocytic, Acute - diagnosis Leukemia, Promyelocytic, Acute - metabolism Leukocyte Common Antigens - chemistry Middle Aged Promyelocytes Protein Isoforms
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