Associations between MUC1 gene polymorphism and resistance to mastitis, milk production and fertility traits in Murrah water buffaloes
MUC1 is a glycoprotein mucin expressed in apical cells of luminal tissues, such as mammary gland luminal cells, which the main function is protect the cell surface from the environment microorganisms. The aim of this study were to identify the polymorphism of MUC1 gene in Murrah breed and to analyze...
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| Veröffentlicht in: | Journal of Applied Animal Research 2020-01, Vol.48 (1), p.151-155 |
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| creator | da Rosa, Fernanda Trindade Moreira, Carla Giovani Avila Barbero, Marina Mortati Dias Hurtado Lugo, Naudin Alejandro de Camargo, Gregório Miguel Ferreira Aspicueta Borquis, Rusbel Raul de Oliveira, Henrique Nunes Boligon, Arione Augusti de Vargas, Lucas Moreira, Heden Luiz Marques Tonhati, Humberto de Souza, Fabio Ricardo Pablos |
| description | MUC1 is a glycoprotein mucin expressed in apical cells of luminal tissues, such as mammary gland luminal cells, which the main function is protect the cell surface from the environment microorganisms. The aim of this study were to identify the polymorphism of MUC1 gene in Murrah breed and to analyze the association between molecular marker and somatic cell counting, milk yield, fat yield, fat percentage, protein yield, protein percentage, age at first calving and calving interval. A total of 179 primiparous Murrah buffaloes were genotyped by PCR technique. Milk-recording were performed periodically to determine fat and protein content and somatic cell count. Three alleles of different lengths were amplified and named allele 1, 2 and 3, respectively. The allele 2 was more frequent followed by allele 3. The MUC1 gene was highly associated with traits related to mastitis resistance and milk percentage. Also was demonstrated a mild association between MUC1 gene and milk protein synthesis and a moderate effect on reproductive trait. The MUC1 gene is polymorphic in water buffaloes of Murrah breed and might be a potential marker to marker-assisted selection for intramammary infection and some milk production traits. |
| doi_str_mv | 10.1080/09712119.2020.1749641 |
| format | Article |
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The aim of this study were to identify the polymorphism of MUC1 gene in Murrah breed and to analyze the association between molecular marker and somatic cell counting, milk yield, fat yield, fat percentage, protein yield, protein percentage, age at first calving and calving interval. A total of 179 primiparous Murrah buffaloes were genotyped by PCR technique. Milk-recording were performed periodically to determine fat and protein content and somatic cell count. Three alleles of different lengths were amplified and named allele 1, 2 and 3, respectively. The allele 2 was more frequent followed by allele 3. The MUC1 gene was highly associated with traits related to mastitis resistance and milk percentage. Also was demonstrated a mild association between MUC1 gene and milk protein synthesis and a moderate effect on reproductive trait. The MUC1 gene is polymorphic in water buffaloes of Murrah breed and might be a potential marker to marker-assisted selection for intramammary infection and some milk production traits.</description><identifier>ISSN: 0971-2119</identifier><identifier>EISSN: 0974-1844</identifier><identifier>DOI: 10.1080/09712119.2020.1749641</identifier><language>eng</language><publisher>Abingdon: Taylor & Francis</publisher><subject>Alleles ; Cell surface ; dairy buffaloes ; Fertility ; Gene polymorphism ; Mammary gland ; Marker-assisted selection ; Mastitis ; Milk production ; Molecular marker ; MUC1 gene ; Mucin ; Polymorphism ; Protein biosynthesis ; Proteins ; VNTR</subject><ispartof>Journal of Applied Animal Research, 2020-01, Vol.48 (1), p.151-155</ispartof><rights>2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group 2020</rights><rights>2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. 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The MUC1 gene is polymorphic in water buffaloes of Murrah breed and might be a potential marker to marker-assisted selection for intramammary infection and some milk production traits.</description><subject>Alleles</subject><subject>Cell surface</subject><subject>dairy buffaloes</subject><subject>Fertility</subject><subject>Gene polymorphism</subject><subject>Mammary gland</subject><subject>Marker-assisted selection</subject><subject>Mastitis</subject><subject>Milk production</subject><subject>Molecular marker</subject><subject>MUC1 gene</subject><subject>Mucin</subject><subject>Polymorphism</subject><subject>Protein biosynthesis</subject><subject>Proteins</subject><subject>VNTR</subject><issn>0971-2119</issn><issn>0974-1844</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>0YH</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><sourceid>DOA</sourceid><recordid>eNp9UcFq3DAQNaWFhjSfUBDkWieSLcvWrWFpm0BCL81ZzNqjRBvb2o5klv2Bfndmd9Meq4uGx5s3M-8VxWclr5Ts5LW0raqUsleVrBhqtTVavSvOGNel6rR-f6xVeSB9LC5S2kh-2taVUWfFn5uUYh8ghzgnsca8Q5zFw-NKiSecUWzjuJ8ibZ9DmgTMgyBMIWWYexQ5iglSDjmkL2IK44vYUhyW_qB15HqkHMaQ9yIThJxEYOmFCJ7FDjKSWC_ewxgxfSo-cJHw4u0_Lx6_f_u1ui3vf_64W93cl71uVC5RowFZ11pqaXtZG2kMnz_Yxqi16Yam9RKNrkFyrZXSFv2ASuqGLRi8rM-Lu5PuEGHjthQmoL2LENwRiPTkgHfuR3Rd57uuXfu2seyiUp0Fa7GDnseDbZG1Lk9afPXvBVN2m7jQzOu7Shu2X5tKM6s5sXqKKRH6f1OVdIcE3d8E3SFB95Yg93099YXZR5pgF2kcXIb9GMkT-x-Sq_8v8Qqzw6Ia</recordid><startdate>20200101</startdate><enddate>20200101</enddate><creator>da Rosa, Fernanda Trindade</creator><creator>Moreira, Carla Giovani Avila</creator><creator>Barbero, Marina Mortati Dias</creator><creator>Hurtado Lugo, Naudin Alejandro</creator><creator>de Camargo, Gregório Miguel Ferreira</creator><creator>Aspicueta Borquis, Rusbel Raul</creator><creator>de Oliveira, Henrique Nunes</creator><creator>Boligon, Arione Augusti</creator><creator>de Vargas, Lucas</creator><creator>Moreira, Heden Luiz Marques</creator><creator>Tonhati, Humberto</creator><creator>de Souza, Fabio Ricardo Pablos</creator><general>Taylor & Francis</general><general>Taylor & Francis Ltd</general><general>Taylor & Francis Group</general><scope>0YH</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7XB</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>DOA</scope></search><sort><creationdate>20200101</creationdate><title>Associations between MUC1 gene polymorphism and resistance to mastitis, milk production and fertility traits in Murrah water buffaloes</title><author>da Rosa, Fernanda Trindade ; 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The aim of this study were to identify the polymorphism of MUC1 gene in Murrah breed and to analyze the association between molecular marker and somatic cell counting, milk yield, fat yield, fat percentage, protein yield, protein percentage, age at first calving and calving interval. A total of 179 primiparous Murrah buffaloes were genotyped by PCR technique. Milk-recording were performed periodically to determine fat and protein content and somatic cell count. Three alleles of different lengths were amplified and named allele 1, 2 and 3, respectively. The allele 2 was more frequent followed by allele 3. The MUC1 gene was highly associated with traits related to mastitis resistance and milk percentage. Also was demonstrated a mild association between MUC1 gene and milk protein synthesis and a moderate effect on reproductive trait. The MUC1 gene is polymorphic in water buffaloes of Murrah breed and might be a potential marker to marker-assisted selection for intramammary infection and some milk production traits.</abstract><cop>Abingdon</cop><pub>Taylor & Francis</pub><doi>10.1080/09712119.2020.1749641</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Alleles Cell surface dairy buffaloes Fertility Gene polymorphism Mammary gland Marker-assisted selection Mastitis Milk production Molecular marker MUC1 gene Mucin Polymorphism Protein biosynthesis Proteins VNTR |
| title | Associations between MUC1 gene polymorphism and resistance to mastitis, milk production and fertility traits in Murrah water buffaloes |
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