Spatial Characterization of Glutathione Depletion in the KHT Sarcoma Using Flow Cytometry

Summary Intravenous administration of the fluorescent DNA stain Hoechst 33342 to tumour-bearing mice was used to label cells proportionally to their proximity from the vasculature. Flow cytometry was used to sort cells from the tumour into populations based on their Hoechst 33342-derived fluorescenc...

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Veröffentlicht in:	International journal of radiation biology 1991, Vol.59 (6), p.1425-1433
Hauptverfasser:	Minchinton, A.I., Chaplin, D.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biological effects of radiation Buthionine Sulfoximine Female Fundamental and applied biological sciences. Psychology Glutathione - biosynthesis Glutathione - physiology Ionizing radiations Methionine Sulfoximine - analogs & derivatives Methionine Sulfoximine - therapeutic use Mice Mice, Inbred C3H Neoplasm Transplantation Radiation Tolerance - drug effects Radiation Tolerance - physiology Sarcoma, Experimental - drug therapy Sarcoma, Experimental - physiopathology Space life sciences Tissues, organs and organisms biophysics
Online-Zugang:	Volltext
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