Neutralization and binding activity of a human single-chain antibody to ricin toxin

Ricin toxin (RT), extracted from castor bean, is a type II ribosome-inactivating protein (RIP). As a biothreat agent, there is no effective antidote for RT to date, but recent advances in antibody research may have meet this need. This study aimed to produce human single-chain antibody variable frag...

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Veröffentlicht in:	Food and agricultural immunology 2020-01, Vol.31 (1), p.63-74
Hauptverfasser:	Yu, Haotian, Chang, Ying, Dong, Mingxin, Wang, Yan, Sun, Chengbiao, Liu, Zhongliang, Wang, Xin, Xu, Na, Liu, Wensen
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antidotes Chains HeLa cells human single-chain antibody variable fragments (HuscFvs) Neutralization Phage display phage library Phages Ribosome-inactivating protein Ricin Ricin toxin Toxins
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