Generation of platelet-derived microparticles and procoagulant activity by heparin-induced thrombocytopenia IgG/serum and other IgG platelet agonists: a comparison with standard platelet agonists

Heparin-induced thrombocytopenia (HIT) is a relatively common, immunoglobulin-mediated adverse drug reaction associated with in vivo thrombin generation and both venous and arterial thrombosis. Serum and purified IgG from patients with HIT induce normal platelets to generate procoagulant platelet-de...

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Veröffentlicht in:	Platelets (Edinburgh) 1999, Vol.10 (5), p.319-326
1. Verfasser:	Sheppard, T.E. Warkentin, J.I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Platelet-derived Microparticles Procoagulant Activity Heparin-induced Thrombocytopenia Igg Platelet Agonists Standard Platelet Agonists
Online-Zugang:	Volltext
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