MicroRNA-23a-3p overexpression represses proliferation and accelerates apoptosis of granular cells in polycystic ovarian syndrome by targeting HMGA2

Granular cells (GCs) are involved in polycystic ovarian syndrome (PCOS) progression. MicroRNA (miR)-23a downregulation is linked to PCOS development. Therefore, this research explored the influences of miR-23a-3p on GC proliferation and apoptosis in PCOS. Reverse transcription-quantitative polymeras...

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Veröffentlicht in:	Gynecological endocrinology 2023-12, Vol.39 (1), p.2172155-2172155
Hauptverfasser:	Wei, Junzi, Cheng, Ping, Kong, Mei, Zhang, Ling, Liu, Shuang, Ning, Bingxue, Huang, Xinlin
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis beta Catenin - genetics Cell Proliferation Female granular cells HMGA2 HMGA2 Protein - metabolism Humans microRNA-23a-3p MicroRNAs - genetics MicroRNAs - metabolism Polycystic ovarian syndrome Polycystic Ovary Syndrome - genetics Polycystic Ovary Syndrome - metabolism Proliferation Wnt/β-catenin pathway
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