Estrogen receptor polymorphisms in tamoxifen-treated women with breast cancer

In postmenopausal women with estrogen receptor (ER)-positive breast cancer, long-term tamoxifen administration has proved beneficial after surgical treatment and subsequent chemotherapy. One of the major adverse effects of tamoxifen is the development of endometrial pathology (polyps, endometrial hy...

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Veröffentlicht in:	Gynecological endocrinology 2006-04, Vol.22 (4), p.185-189
Hauptverfasser:	Georgopoulos, Neoklis A., Adonakis, George L., Fotopoulos, Andreas, Koika, Vasiliki, Spinos, Nikitas, Saltamavros, Alexandros, Keramopoulos, Antonios, Koukouras, Dimitrios, Decavalas, George, Kourounis, George S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Endometrial Neoplasms - etiology Endometrial Neoplasms - pathology endometrial pathology Endometrium - pathology Estrogen Receptor alpha - genetics Estrogen Receptor beta - genetics Estrogen receptor polymorphisms estrogen receptor-α estrogen receptor-β Female Genetic Predisposition to Disease Humans Middle Aged Neoplasm Staging - adverse effects Polymorphism, Genetic - genetics Selective Estrogen Receptor Modulators - adverse effects tamoxifen Tamoxifen - adverse effects
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