The multi-herbal formula Chong-Myung-Tang improves spatial memory and increases cell genesis in the dentate gyrus of aged mice

Chong-Myung-Tang (CMT) is a multi-herbal formula that has been used to improve memory. However, the potential mechanism remains unknown. The present study investigated the effects of CMT (50, 100, and 200 mg/kg) on spatial memory of aged mice. The behavioral training tests indicated that 200 mg/kg C...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2014-10, Vol.78 (10), p.1710-1715
Hauptverfasser:	Liu, Lei, Zhang, Mingwei, Zhang, Ruifen, Lee, Mira, Wang, Zhen, Hou, Jingang, Sung, Chang-Keun
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology Animals Behavior, Animal - drug effects Behavior, Animal - physiology cell proliferation Cell Proliferation - drug effects cell survival Cell Survival - drug effects Chemistry, Pharmaceutical Chong-Myung-Tang dentate gyrus Dentate Gyrus - cytology Dentate Gyrus - drug effects Dentate Gyrus - physiology Male Maze Learning - drug effects Mice Mice, Inbred ICR Neurogenesis - drug effects Plant Extracts - chemistry Plant Extracts - pharmacology spatial memory Spatial Memory - drug effects
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