Insulin-like growth factor II mediates resveratrol stimulatory effect on cathepsin D in breast cancer cells

Cathepsin D (CD) is an enzyme that promotes breast cancer. CD is stored intracellularly; however, we demonstrated that IGF-II promotes CD secretion in estrogen receptor positive (ER+) breast cancer cells. We also showed that resveratrol (RSV) stimulates IGF-II in ER(+) breast cancer cells. Thus, we...

Ausführliche Beschreibung