Synthesis of Thymine Nucleosides Derived from 1-Deoxy-D-psicofuranose

The use of D-(+)-ribonic γ-lactone 1a,b as a chiral synthon leads to an efficient synthesis of the ketose 1-deoxy-D-psicofuranose 2a,b. Condensation of the corresponding acetyl derivative 3a,b with silylated thymine, followed by deprotection of 4a,b affords an anomeric mixture of ketosyl nucleoside...

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Veröffentlicht in:	Nucleosides & nucleotides 1992-11, Vol.11 (9), p.1651-1660
Hauptverfasser:	Faivre-Buet, Véronique, Grouiller, Annie, Descotes, Gérard
Format:	Artikel
Sprache:	eng
Schlagworte:	Carbohydrates. Nucleosides and nucleotides Chemistry Exact sciences and technology Nucleosides, nucleotides and oligonucleotides Organic chemistry Preparations and properties
Online-Zugang:	Volltext
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