Analogues of Moranoline and Mdl 73945. Methyl 6(5)-Deoxy-6(5)-(Morpholin-4-Yl)-α-D-Glycosides as Glucosidase Inhibitors

Methyl 2,3,4-tri-O-acetyl-6-O-(p-tolylsulfonyl)-α-D-glucopyranoside (6), or its iodo analogue 7, were subjected to nucleophilic displacement with morpholine to give 8, deacetylation of which gave methyl 6-deoxy-6-(morpholin-4-yl)-α-D-glucopyranoside (3). Similarly, 11, 12 and 21 were prepared. The 6...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of carbohydrate chemistry 2000-01, Vol.19 (3), p.345-357
Hauptverfasser:	El Ashry, El Sayed H., Abdel-Rahman, Adel A.-H., Kattab, Mohamed, Shobier, Aida H., Schmidt, Richard R.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!