Matrix metalloproteinase enzyme responsive delivery of 5-Fluorouracil using Collagen-I peptide functionalized Dendrimer-Gold nanocarrier

The aim was to develop matrix metalloproteinase 1 (MMP1) responsive nanoparticle system for the delivery of 5-fluorouracil (5Fu) anticancer drug. The MMP1 in the cancer microenvironment-induced drug release have the advantage of targeted drug release and reduce the distribution of drug to the health...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Drug development and industrial pharmacy 2022-07, Vol.48 (7), p.333-342
Hauptverfasser:	Chauhan, Sejal, Patel, Krunal, Jain, Poonam, Jangid, Ashok Kumar, Patel, Sunita, Medicherla, Kanakaraju, Limbad, Kajal, Mehta, Chetan, Kulhari, Hitesh
Format:	Artikel
Sprache:	eng
Schlagworte:	5-fluorouracil dendrimers Enzyme-responsive gold nanoparticles MMP1 theranostic nanoparticles
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!