Reduction in Dose from CT Examinations of Liver Lesions with a New Postprocessing Filter: A ROC Phantom Study
Background: It is desirable to lower the dose from computed tomography (CT) examinations as much as possible without reducing diagnostic performance. Mathematical postprocessing filters are one tool to achieve dose reduction. Purpose: To evaluate the possibilities of reducing CT doses from liver exa...
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| Veröffentlicht in: | Acta radiologica (1987) 2008-04, Vol.49 (3), p.303-309 |
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| container_title | Acta radiologica (1987) |
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| creator | Martinsen, A. C. Trægde Sæther, H. Kjernlie Olsen, D. R. Skaane, P. Olerud, H. M. |
| description | Background: It is desirable to lower the dose from computed tomography (CT) examinations as much as possible without reducing diagnostic performance. Mathematical postprocessing filters are one tool to achieve dose reduction.
Purpose: To evaluate the possibilities of reducing CT doses from liver examinations using a new postprocessing filter.
Material and Methods: An anthropomorphic upper-abdomen phantom was used in receiver operating characteristic (ROC) studies of the detectability of liver lesions. A standard abdominal CT protocol was used. Only mA settings were changed; all other scan parameters were constant. The postprocessing filter used was SharpView CT, which provides context-controlled restoration of digital images using adaptive filters. Six readers were given a set of 10 images obtained at five different dose levels, each image with 32 predefined areas to be evaluated on a five-point scale. In total, 1920 areas were evaluated. At each dose level, the readers evaluated five images without enhancement and five images based on postprocessing filters. All images were randomized with respect to dose level.
Results: The postprocessing filter improved the diagnostic performance significantly compared to the unenhanced images at all dose levels. Radiation dose for abdominal CT examinations of liver lesions in the range 2-7 mm was reduced by 30% using postprocessing filters, while diagnostic performance of the examination was maintained or even improved.
Conclusion: This study indicates great potential for lowering doses for CT examinations of liver lesions using the new postprocessing filter. The software must be fully tested clinically to reliably assess the benefits of this filtration. |
| doi_str_mv | 10.1080/02841850701793769 |
| format | Article |
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Purpose: To evaluate the possibilities of reducing CT doses from liver examinations using a new postprocessing filter.
Material and Methods: An anthropomorphic upper-abdomen phantom was used in receiver operating characteristic (ROC) studies of the detectability of liver lesions. A standard abdominal CT protocol was used. Only mA settings were changed; all other scan parameters were constant. The postprocessing filter used was SharpView CT, which provides context-controlled restoration of digital images using adaptive filters. Six readers were given a set of 10 images obtained at five different dose levels, each image with 32 predefined areas to be evaluated on a five-point scale. In total, 1920 areas were evaluated. At each dose level, the readers evaluated five images without enhancement and five images based on postprocessing filters. All images were randomized with respect to dose level.
Results: The postprocessing filter improved the diagnostic performance significantly compared to the unenhanced images at all dose levels. Radiation dose for abdominal CT examinations of liver lesions in the range 2-7 mm was reduced by 30% using postprocessing filters, while diagnostic performance of the examination was maintained or even improved.
Conclusion: This study indicates great potential for lowering doses for CT examinations of liver lesions using the new postprocessing filter. The software must be fully tested clinically to reliably assess the benefits of this filtration.</description><identifier>ISSN: 0284-1851</identifier><identifier>EISSN: 1600-0455</identifier><identifier>DOI: 10.1080/02841850701793769</identifier><identifier>PMID: 18365819</identifier><identifier>CODEN: ACRAE3</identifier><language>eng</language><publisher>London, England: Informa UK Ltd</publisher><subject>Biological and medical sciences ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; Liver Neoplasms - diagnostic imaging ; Medical sciences ; Observer Variation ; Phantoms, Imaging ; Radiation Dosage ; Radiographic Image Interpretation, Computer-Assisted - instrumentation ; Radiographic Image Interpretation, Computer-Assisted - methods ; Radiography, Abdominal - instrumentation ; Radiography, Abdominal - methods ; ROC Curve ; Tomography, X-Ray Computed - instrumentation ; Tomography, X-Ray Computed - methods</subject><ispartof>Acta radiologica (1987), 2008-04, Vol.49 (3), p.303-309</ispartof><rights>2008 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2008</rights><rights>Informa UK Ltd. (Informa Healthcare, Taylor & Francis AS)</rights><rights>2009 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c463t-ce12df49f9efb7985de065e27be3799702f03792d72ad015980575a24df78b403</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/02841850701793769$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/02841850701793769$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,61198,61379</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21138295$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18365819$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Martinsen, A. C. Trægde</creatorcontrib><creatorcontrib>Sæther, H. Kjernlie</creatorcontrib><creatorcontrib>Olsen, D. R.</creatorcontrib><creatorcontrib>Skaane, P.</creatorcontrib><creatorcontrib>Olerud, H. M.</creatorcontrib><title>Reduction in Dose from CT Examinations of Liver Lesions with a New Postprocessing Filter: A ROC Phantom Study</title><title>Acta radiologica (1987)</title><addtitle>Acta Radiol</addtitle><description>Background: It is desirable to lower the dose from computed tomography (CT) examinations as much as possible without reducing diagnostic performance. Mathematical postprocessing filters are one tool to achieve dose reduction.
Purpose: To evaluate the possibilities of reducing CT doses from liver examinations using a new postprocessing filter.
Material and Methods: An anthropomorphic upper-abdomen phantom was used in receiver operating characteristic (ROC) studies of the detectability of liver lesions. A standard abdominal CT protocol was used. Only mA settings were changed; all other scan parameters were constant. The postprocessing filter used was SharpView CT, which provides context-controlled restoration of digital images using adaptive filters. Six readers were given a set of 10 images obtained at five different dose levels, each image with 32 predefined areas to be evaluated on a five-point scale. In total, 1920 areas were evaluated. At each dose level, the readers evaluated five images without enhancement and five images based on postprocessing filters. All images were randomized with respect to dose level.
Results: The postprocessing filter improved the diagnostic performance significantly compared to the unenhanced images at all dose levels. Radiation dose for abdominal CT examinations of liver lesions in the range 2-7 mm was reduced by 30% using postprocessing filters, while diagnostic performance of the examination was maintained or even improved.
Conclusion: This study indicates great potential for lowering doses for CT examinations of liver lesions using the new postprocessing filter. The software must be fully tested clinically to reliably assess the benefits of this filtration.</description><subject>Biological and medical sciences</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Liver Neoplasms - diagnostic imaging</subject><subject>Medical sciences</subject><subject>Observer Variation</subject><subject>Phantoms, Imaging</subject><subject>Radiation Dosage</subject><subject>Radiographic Image Interpretation, Computer-Assisted - instrumentation</subject><subject>Radiographic Image Interpretation, Computer-Assisted - methods</subject><subject>Radiography, Abdominal - instrumentation</subject><subject>Radiography, Abdominal - methods</subject><subject>ROC Curve</subject><subject>Tomography, X-Ray Computed - instrumentation</subject><subject>Tomography, X-Ray Computed - methods</subject><issn>0284-1851</issn><issn>1600-0455</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMtOwzAQRS0EgvL4ADbIG5aBsRPHNqxQKQ-poojHOnKTMTVq4spOKfw9Ka1ggYRYeeQ5Z0ZzCTlkcMJAwSlwlTElQAKTOpW53iA9lgMkkAmxSXrLftIBbIfsxvgKwLgUbJvsMJXmQjHdI_UDVvOydb6hrqGXPiK1wde0_0QH76Z2jVn2IvWWDt0bBjrE-PWxcO2EGnqHC3rvYzsLvsQYXfNCr9y0xXBGL-jDqE_vJ6Zpu4GP7bz62Cdb1kwjHqzfPfJ8NXjq3yTD0fVt_2KYlFmetkmJjFc201ajHUutRIWQC-RyjKnUWgK30BW8ktxUwIRWIKQwPKusVOMM0j3CVnPL4GMMaItZcLUJHwWDYhld8Su6zjlaObP5uMbqx1hn1QHHa8DE0kxtME3p4jfHGUsV16LjTlZcNC9YvPp5aLpb_9x8vhJcY32ozQTNtJ2UJvzL_gQrYJTl</recordid><startdate>200804</startdate><enddate>200804</enddate><creator>Martinsen, A. C. Trægde</creator><creator>Sæther, H. Kjernlie</creator><creator>Olsen, D. R.</creator><creator>Skaane, P.</creator><creator>Olerud, H. M.</creator><general>Informa UK Ltd</general><general>SAGE Publications</general><general>Royal Society of Medicine</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>200804</creationdate><title>Reduction in Dose from CT Examinations of Liver Lesions with a New Postprocessing Filter: A ROC Phantom Study</title><author>Martinsen, A. C. Trægde ; Sæther, H. Kjernlie ; Olsen, D. R. ; Skaane, P. ; Olerud, H. M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c463t-ce12df49f9efb7985de065e27be3799702f03792d72ad015980575a24df78b403</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Biological and medical sciences</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Liver Neoplasms - diagnostic imaging</topic><topic>Medical sciences</topic><topic>Observer Variation</topic><topic>Phantoms, Imaging</topic><topic>Radiation Dosage</topic><topic>Radiographic Image Interpretation, Computer-Assisted - instrumentation</topic><topic>Radiographic Image Interpretation, Computer-Assisted - methods</topic><topic>Radiography, Abdominal - instrumentation</topic><topic>Radiography, Abdominal - methods</topic><topic>ROC Curve</topic><topic>Tomography, X-Ray Computed - instrumentation</topic><topic>Tomography, X-Ray Computed - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Martinsen, A. C. Trægde</creatorcontrib><creatorcontrib>Sæther, H. Kjernlie</creatorcontrib><creatorcontrib>Olsen, D. R.</creatorcontrib><creatorcontrib>Skaane, P.</creatorcontrib><creatorcontrib>Olerud, H. M.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Acta radiologica (1987)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Martinsen, A. C. Trægde</au><au>Sæther, H. Kjernlie</au><au>Olsen, D. R.</au><au>Skaane, P.</au><au>Olerud, H. M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reduction in Dose from CT Examinations of Liver Lesions with a New Postprocessing Filter: A ROC Phantom Study</atitle><jtitle>Acta radiologica (1987)</jtitle><addtitle>Acta Radiol</addtitle><date>2008-04</date><risdate>2008</risdate><volume>49</volume><issue>3</issue><spage>303</spage><epage>309</epage><pages>303-309</pages><issn>0284-1851</issn><eissn>1600-0455</eissn><coden>ACRAE3</coden><abstract>Background: It is desirable to lower the dose from computed tomography (CT) examinations as much as possible without reducing diagnostic performance. Mathematical postprocessing filters are one tool to achieve dose reduction.
Purpose: To evaluate the possibilities of reducing CT doses from liver examinations using a new postprocessing filter.
Material and Methods: An anthropomorphic upper-abdomen phantom was used in receiver operating characteristic (ROC) studies of the detectability of liver lesions. A standard abdominal CT protocol was used. Only mA settings were changed; all other scan parameters were constant. The postprocessing filter used was SharpView CT, which provides context-controlled restoration of digital images using adaptive filters. Six readers were given a set of 10 images obtained at five different dose levels, each image with 32 predefined areas to be evaluated on a five-point scale. In total, 1920 areas were evaluated. At each dose level, the readers evaluated five images without enhancement and five images based on postprocessing filters. All images were randomized with respect to dose level.
Results: The postprocessing filter improved the diagnostic performance significantly compared to the unenhanced images at all dose levels. Radiation dose for abdominal CT examinations of liver lesions in the range 2-7 mm was reduced by 30% using postprocessing filters, while diagnostic performance of the examination was maintained or even improved.
Conclusion: This study indicates great potential for lowering doses for CT examinations of liver lesions using the new postprocessing filter. The software must be fully tested clinically to reliably assess the benefits of this filtration.</abstract><cop>London, England</cop><pub>Informa UK Ltd</pub><pmid>18365819</pmid><doi>10.1080/02841850701793769</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Acta radiologica (1987), 2008-04, Vol.49 (3), p.303-309 |
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| source | MEDLINE; Taylor & Francis Journals Complete |
| subjects | Biological and medical sciences Humans Investigative techniques, diagnostic techniques (general aspects) Liver Neoplasms - diagnostic imaging Medical sciences Observer Variation Phantoms, Imaging Radiation Dosage Radiographic Image Interpretation, Computer-Assisted - instrumentation Radiographic Image Interpretation, Computer-Assisted - methods Radiography, Abdominal - instrumentation Radiography, Abdominal - methods ROC Curve Tomography, X-Ray Computed - instrumentation Tomography, X-Ray Computed - methods |
| title | Reduction in Dose from CT Examinations of Liver Lesions with a New Postprocessing Filter: A ROC Phantom Study |
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