L-Carnitine Protects Human Retinal Pigment Epithelial Cells from Oxidative Damage

Purpose: To determine the efficacy of L-carnitine (LC) against oxidative changes in human retinal pigment epithelium (RPE) cells. Methods: The RPE cells from human donor eyes were cultured in Hams F-10 medium. The effect of LC on H2O2-induced morphologic changes in the RPE cells was analyzed by ligh...

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Veröffentlicht in:	Current eye research 2007-01, Vol.32 (6), p.575-584
Hauptverfasser:	Shamsi, Farrukh A., Chaudhry, Imtiaz A., Boulton, Mike E., Al-Rajhi, Ali A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult aging Carnitine - pharmacology Cell Survival Cells, Cultured Cytoprotection - drug effects enzymes Formazans Glutathione - metabolism Humans Hydrogen Peroxide - toxicity L-carnitine Middle Aged morphology Oxidants - toxicity oxidation Oxidative Stress Pigment Epithelium of Eye - drug effects Pigment Epithelium of Eye - enzymology Pigment Epithelium of Eye - pathology RPE Superoxide Dismutase - metabolism Tetrazolium Salts Vitamin B Complex - pharmacology
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