Comparison of in vivo fate and immunogenicity of hepatitis B surface antigen incorporated in cationic and neutral liposomes

To compare cationic liposomes (CatL) and neutral liposomes (NeuL), as a vaccine carrier, the in vivo fate and immunogenicity of hepatitis B surface antigen (HBsAg), incorporated in CatL and NeuL, were investigated. CatL, composed of phosphatidyl choline (PC) and stearyl amine (SA) with a molar ratio...

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Veröffentlicht in:	Journal of microencapsulation 2000-05, Vol.17 (3), p.297-306
Hauptverfasser:	KIM, C.-K, JEONG, E. J, KIM, M.-H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic Animals Antibody Formation - immunology Area Under Curve Biological and medical sciences Cationic Liposomes Neutral Liposomes Hepatitis B Surface Antigen Immunoadjuvant Vaccine Carrier Cations Drug Carriers General pharmacology Hepatitis B Surface Antigens - administration & dosage Hepatitis B Surface Antigens - immunology Hypersensitivity, Delayed - immunology Immunomodulators Injections, Intramuscular Iodine Radioisotopes Liposomes Male Medical sciences Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Rats Rats, Wistar
Online-Zugang:	Volltext
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