Functional testing and chemical composition of cryptococcal extracts
Three antigens were compared for their ability to detect immune responses in C57B1/6 mice sensitized to Cryptococcus neoformans. Elicitation of responses in vitro was greatest with a urea extract antigen, followed in efficiency by an alkali extract and a soluble capsular polysaccharide preparation....
Gespeichert in:
| Veröffentlicht in: | Medical mycology (Oxford) 1984, Vol.22 (5), p.439-442 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 442 |
|---|---|
| container_issue | 5 |
| container_start_page | 439 |
| container_title | Medical mycology (Oxford) |
| container_volume | 22 |
| creator | Hall, Nancy K. Maluf, Karen C. Blackstock, Rebecca |
| description | Three antigens were compared for their ability to detect immune responses in C57B1/6 mice sensitized to Cryptococcus neoformans. Elicitation of responses in vitro was greatest with a urea extract antigen, followed in efficiency by an alkali extract and a soluble capsular polysaccharide preparation. The reactivity paralleled the protein content of the preparation.
ZUSAMMENFASSUNG
Drei Antigene wurden auf ihre Fähigkeit, eine Immunantwort bei mit Cryptococcus neoformans sensibilisierten C57B1/6 Mäusen zu entdecken, vergleichend geprüft. Die beste in vitro Immunantwort wurde ausgelöst durch ein Harnstoffextrakt, gefolgt von einem Alkali-Extrakt und einem löslichen Polysaccharid-Kapselpräparat. Die Reaktivität korrelierte mit dem Proteingehalt des Antigens. |
| doi_str_mv | 10.1080/00362178485380701 |
| format | Article |
| fullrecord | <record><control><sourceid>informahealthcare_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1080_00362178485380701</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_1080_00362178485380701</sourcerecordid><originalsourceid>FETCH-LOGICAL-c164t-ac02ef3e1f753d969c8bbc78de1409ec63f6ecf3ad183079c31157e81ed332593</originalsourceid><addsrcrecordid>eNp9kE9Lw0AQxRdRsFY_gLd8gehMNtk_eJJqVSh40XPYTmZtSpMtu1uw396WehM8veG9-Q3ME-IW4Q7BwD2AVBVqU5tGGtCAZ2KCtYKy0mDPD7NUtpTaqEtxldIaALWt5EQ8zXcj5T6MblNkTrkfvwo3dgWteOjpYFIYtiH1x5Ui-ILifpsDBTpm_J2jo5yuxYV3m8Q3vzoVn_Pnj9lruXh_eZs9LkpCVefSEVTsJaPXjeyssmSWS9KmY6zBMinpFZOXrkMjQVuSiI1mg9xJWTVWTgWe7lIMKUX27Tb2g4v7FqE91tD-qeHAPJyYfvQhDm7FbpNX5CK367CLh7_TP_QPfnxjOQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Functional testing and chemical composition of cryptococcal extracts</title><source>Taylor & Francis:Master (3349 titles)</source><creator>Hall, Nancy K. ; Maluf, Karen C. ; Blackstock, Rebecca</creator><creatorcontrib>Hall, Nancy K. ; Maluf, Karen C. ; Blackstock, Rebecca</creatorcontrib><description>Three antigens were compared for their ability to detect immune responses in C57B1/6 mice sensitized to Cryptococcus neoformans. Elicitation of responses in vitro was greatest with a urea extract antigen, followed in efficiency by an alkali extract and a soluble capsular polysaccharide preparation. The reactivity paralleled the protein content of the preparation.
ZUSAMMENFASSUNG
Drei Antigene wurden auf ihre Fähigkeit, eine Immunantwort bei mit Cryptococcus neoformans sensibilisierten C57B1/6 Mäusen zu entdecken, vergleichend geprüft. Die beste in vitro Immunantwort wurde ausgelöst durch ein Harnstoffextrakt, gefolgt von einem Alkali-Extrakt und einem löslichen Polysaccharid-Kapselpräparat. Die Reaktivität korrelierte mit dem Proteingehalt des Antigens.</description><identifier>ISSN: 1369-3786</identifier><identifier>EISSN: 1460-2709</identifier><identifier>DOI: 10.1080/00362178485380701</identifier><language>eng</language><publisher>Informa UK Ltd</publisher><ispartof>Medical mycology (Oxford), 1984, Vol.22 (5), p.439-442</ispartof><rights>1984 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1984</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c164t-ac02ef3e1f753d969c8bbc78de1409ec63f6ecf3ad183079c31157e81ed332593</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/00362178485380701$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/00362178485380701$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,777,781,4010,27904,27905,27906,61200,61381</link.rule.ids></links><search><creatorcontrib>Hall, Nancy K.</creatorcontrib><creatorcontrib>Maluf, Karen C.</creatorcontrib><creatorcontrib>Blackstock, Rebecca</creatorcontrib><title>Functional testing and chemical composition of cryptococcal extracts</title><title>Medical mycology (Oxford)</title><description>Three antigens were compared for their ability to detect immune responses in C57B1/6 mice sensitized to Cryptococcus neoformans. Elicitation of responses in vitro was greatest with a urea extract antigen, followed in efficiency by an alkali extract and a soluble capsular polysaccharide preparation. The reactivity paralleled the protein content of the preparation.
ZUSAMMENFASSUNG
Drei Antigene wurden auf ihre Fähigkeit, eine Immunantwort bei mit Cryptococcus neoformans sensibilisierten C57B1/6 Mäusen zu entdecken, vergleichend geprüft. Die beste in vitro Immunantwort wurde ausgelöst durch ein Harnstoffextrakt, gefolgt von einem Alkali-Extrakt und einem löslichen Polysaccharid-Kapselpräparat. Die Reaktivität korrelierte mit dem Proteingehalt des Antigens.</description><issn>1369-3786</issn><issn>1460-2709</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><recordid>eNp9kE9Lw0AQxRdRsFY_gLd8gehMNtk_eJJqVSh40XPYTmZtSpMtu1uw396WehM8veG9-Q3ME-IW4Q7BwD2AVBVqU5tGGtCAZ2KCtYKy0mDPD7NUtpTaqEtxldIaALWt5EQ8zXcj5T6MblNkTrkfvwo3dgWteOjpYFIYtiH1x5Ui-ILifpsDBTpm_J2jo5yuxYV3m8Q3vzoVn_Pnj9lruXh_eZs9LkpCVefSEVTsJaPXjeyssmSWS9KmY6zBMinpFZOXrkMjQVuSiI1mg9xJWTVWTgWe7lIMKUX27Tb2g4v7FqE91tD-qeHAPJyYfvQhDm7FbpNX5CK367CLh7_TP_QPfnxjOQ</recordid><startdate>1984</startdate><enddate>1984</enddate><creator>Hall, Nancy K.</creator><creator>Maluf, Karen C.</creator><creator>Blackstock, Rebecca</creator><general>Informa UK Ltd</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>1984</creationdate><title>Functional testing and chemical composition of cryptococcal extracts</title><author>Hall, Nancy K. ; Maluf, Karen C. ; Blackstock, Rebecca</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c164t-ac02ef3e1f753d969c8bbc78de1409ec63f6ecf3ad183079c31157e81ed332593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hall, Nancy K.</creatorcontrib><creatorcontrib>Maluf, Karen C.</creatorcontrib><creatorcontrib>Blackstock, Rebecca</creatorcontrib><collection>CrossRef</collection><jtitle>Medical mycology (Oxford)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hall, Nancy K.</au><au>Maluf, Karen C.</au><au>Blackstock, Rebecca</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Functional testing and chemical composition of cryptococcal extracts</atitle><jtitle>Medical mycology (Oxford)</jtitle><date>1984</date><risdate>1984</risdate><volume>22</volume><issue>5</issue><spage>439</spage><epage>442</epage><pages>439-442</pages><issn>1369-3786</issn><eissn>1460-2709</eissn><abstract>Three antigens were compared for their ability to detect immune responses in C57B1/6 mice sensitized to Cryptococcus neoformans. Elicitation of responses in vitro was greatest with a urea extract antigen, followed in efficiency by an alkali extract and a soluble capsular polysaccharide preparation. The reactivity paralleled the protein content of the preparation.
ZUSAMMENFASSUNG
Drei Antigene wurden auf ihre Fähigkeit, eine Immunantwort bei mit Cryptococcus neoformans sensibilisierten C57B1/6 Mäusen zu entdecken, vergleichend geprüft. Die beste in vitro Immunantwort wurde ausgelöst durch ein Harnstoffextrakt, gefolgt von einem Alkali-Extrakt und einem löslichen Polysaccharid-Kapselpräparat. Die Reaktivität korrelierte mit dem Proteingehalt des Antigens.</abstract><pub>Informa UK Ltd</pub><doi>10.1080/00362178485380701</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1369-3786 |
| ispartof | Medical mycology (Oxford), 1984, Vol.22 (5), p.439-442 |
| issn | 1369-3786 1460-2709 |
| language | eng |
| recordid | cdi_crossref_primary_10_1080_00362178485380701 |
| source | Taylor & Francis:Master (3349 titles) |
| title | Functional testing and chemical composition of cryptococcal extracts |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-18T11%3A50%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-informahealthcare_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Functional%20testing%20and%20chemical%20composition%20of%20cryptococcal%20extracts&rft.jtitle=Medical%20mycology%20(Oxford)&rft.au=Hall,%20Nancy%20K.&rft.date=1984&rft.volume=22&rft.issue=5&rft.spage=439&rft.epage=442&rft.pages=439-442&rft.issn=1369-3786&rft.eissn=1460-2709&rft_id=info:doi/10.1080/00362178485380701&rft_dat=%3Cinformahealthcare_cross%3E10_1080_00362178485380701%3C/informahealthcare_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |