Locomotor Analysis of the Taiep Rat
Locomotor activity (tremor, ataxia, immobility, epilepsy, and paralysis) in the taiep rat, which suffers from a myelin deficient disorder, has not been previously documented. This study used walking track analysis of footprints to analyze locomotor activity in the taiep rat in comparison to normal,...
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Veröffentlicht in: | The Journal of general psychology 2000-10, Vol.127 (4), p.412-425 |
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creator | Anch, A. M. Powell, E. Bloom, C. Dyche, J. Faulkner, K. Richter, R. R. |
description | Locomotor activity (tremor, ataxia, immobility, epilepsy, and paralysis) in the taiep rat, which suffers from a myelin deficient disorder, has not been previously documented. This study used walking track analysis of footprints to analyze locomotor activity in the taiep rat in comparison to normal, age-matched controls. The results confirmed differences between normal and taiep rats in terms of stride length, step length, and stride width. In addition, we found significant interactions between age and condition for stride and step length. The results suggest that locomotor analysis is a sensitive indicant of myelin deficiency. The results are discussed in terms of the underlying myelin deficiency and possible treatment regimens. |
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M. ; Powell, E. ; Bloom, C. ; Dyche, J. ; Faulkner, K. ; Richter, R. R.</creator><creatorcontrib>Anch, A. M. ; Powell, E. ; Bloom, C. ; Dyche, J. ; Faulkner, K. ; Richter, R. R.</creatorcontrib><description>Locomotor activity (tremor, ataxia, immobility, epilepsy, and paralysis) in the taiep rat, which suffers from a myelin deficient disorder, has not been previously documented. This study used walking track analysis of footprints to analyze locomotor activity in the taiep rat in comparison to normal, age-matched controls. The results confirmed differences between normal and taiep rats in terms of stride length, step length, and stride width. In addition, we found significant interactions between age and condition for stride and step length. The results suggest that locomotor analysis is a sensitive indicant of myelin deficiency. The results are discussed in terms of the underlying myelin deficiency and possible treatment regimens.</description><identifier>ISSN: 0022-1309</identifier><identifier>EISSN: 1940-0888</identifier><identifier>DOI: 10.1080/00221300009598594</identifier><identifier>PMID: 11110003</identifier><identifier>CODEN: JGPSAY</identifier><language>eng</language><publisher>United States: Taylor & Francis Group</publisher><subject>Age groups ; Animals ; Ataxia ; Data collection ; Disease ; Epilepsy ; locomotor activity ; Longitudinal studies ; Motor ability ; Movement Disorders - diagnosis ; Movement Disorders - etiology ; Movement Disorders - physiopathology ; myelin deficiency ; Myelin Sheath - pathology ; neurodegenerative disease ; Neurodegenerative Diseases - complications ; Neurodegenerative Diseases - pathology ; Neurological disorders ; rat ; Rats ; Rats, Sprague-Dawley ; Rodents</subject><ispartof>The Journal of general psychology, 2000-10, Vol.127 (4), p.412-425</ispartof><rights>Copyright Taylor & Francis Group, LLC 2000</rights><rights>Copyright HELDREF PUBLICATIONS Oct 2000</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c453t-7f9ad68c085ca1459a866a2d1a509d1981532dd061008031c2f4841f20387c4b3</citedby><cites>FETCH-LOGICAL-c453t-7f9ad68c085ca1459a866a2d1a509d1981532dd061008031c2f4841f20387c4b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27874,27929,27930</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11110003$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Anch, A. M.</creatorcontrib><creatorcontrib>Powell, E.</creatorcontrib><creatorcontrib>Bloom, C.</creatorcontrib><creatorcontrib>Dyche, J.</creatorcontrib><creatorcontrib>Faulkner, K.</creatorcontrib><creatorcontrib>Richter, R. R.</creatorcontrib><title>Locomotor Analysis of the Taiep Rat</title><title>The Journal of general psychology</title><addtitle>J Gen Psychol</addtitle><description>Locomotor activity (tremor, ataxia, immobility, epilepsy, and paralysis) in the taiep rat, which suffers from a myelin deficient disorder, has not been previously documented. This study used walking track analysis of footprints to analyze locomotor activity in the taiep rat in comparison to normal, age-matched controls. The results confirmed differences between normal and taiep rats in terms of stride length, step length, and stride width. In addition, we found significant interactions between age and condition for stride and step length. The results suggest that locomotor analysis is a sensitive indicant of myelin deficiency. The results are discussed in terms of the underlying myelin deficiency and possible treatment regimens.</description><subject>Age groups</subject><subject>Animals</subject><subject>Ataxia</subject><subject>Data collection</subject><subject>Disease</subject><subject>Epilepsy</subject><subject>locomotor activity</subject><subject>Longitudinal studies</subject><subject>Motor ability</subject><subject>Movement Disorders - diagnosis</subject><subject>Movement Disorders - etiology</subject><subject>Movement Disorders - physiopathology</subject><subject>myelin deficiency</subject><subject>Myelin Sheath - pathology</subject><subject>neurodegenerative disease</subject><subject>Neurodegenerative Diseases - complications</subject><subject>Neurodegenerative Diseases - pathology</subject><subject>Neurological disorders</subject><subject>rat</subject><subject>Rats</subject><subject>Rats, Sprague-Dawley</subject><subject>Rodents</subject><issn>0022-1309</issn><issn>1940-0888</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>0R3</sourceid><sourceid>ACFII</sourceid><sourceid>HYQOX</sourceid><sourceid>K30</sourceid><sourceid>~OC</sourceid><sourceid>~PJ</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkFtLAzEQhYMotlZ_gC-yWPBtdXLbTcCXUrxBQZD6HNLsBrfsbmqyi_bfm9KCYFHnZRjmO2eGg9A5hmsMAm4ACMEUYkkuBZfsAA2xZJCCEOIQDTf7NAJygE5CWMJmzukxGuBYcaJDNJ454xrXOZ9MWl2vQxUSZ5PurUzmuipXyYvuTtGR1XUoz3Z9hF7v7-bTx3T2_PA0ncxSwzjt0txKXWTCgOBGY8alFlmmSYE1B1lgKTCnpCggi6cFUGyIZYJhS4CK3LAFHaGrre_Ku_e-DJ1qqmDKutZt6fqgcsJyCjiP4OUPcOl6H98PKuaRccgYidD4NwgTCRlwQnGk8JYy3oXgS6tWvmq0XysMahOy2gs5ai52zv2iKYtvxS7VCNxugaq1zjf6w_m6UJ1e185br1tTBUX_8s__le-pVPfZ0S9L3JaX</recordid><startdate>20001001</startdate><enddate>20001001</enddate><creator>Anch, A. 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M.</au><au>Powell, E.</au><au>Bloom, C.</au><au>Dyche, J.</au><au>Faulkner, K.</au><au>Richter, R. R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Locomotor Analysis of the Taiep Rat</atitle><jtitle>The Journal of general psychology</jtitle><addtitle>J Gen Psychol</addtitle><date>2000-10-01</date><risdate>2000</risdate><volume>127</volume><issue>4</issue><spage>412</spage><epage>425</epage><pages>412-425</pages><issn>0022-1309</issn><eissn>1940-0888</eissn><coden>JGPSAY</coden><abstract>Locomotor activity (tremor, ataxia, immobility, epilepsy, and paralysis) in the taiep rat, which suffers from a myelin deficient disorder, has not been previously documented. This study used walking track analysis of footprints to analyze locomotor activity in the taiep rat in comparison to normal, age-matched controls. The results confirmed differences between normal and taiep rats in terms of stride length, step length, and stride width. In addition, we found significant interactions between age and condition for stride and step length. The results suggest that locomotor analysis is a sensitive indicant of myelin deficiency. The results are discussed in terms of the underlying myelin deficiency and possible treatment regimens.</abstract><cop>United States</cop><pub>Taylor & Francis Group</pub><pmid>11110003</pmid><doi>10.1080/00221300009598594</doi><tpages>14</tpages></addata></record> |
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subjects | Age groups Animals Ataxia Data collection Disease Epilepsy locomotor activity Longitudinal studies Motor ability Movement Disorders - diagnosis Movement Disorders - etiology Movement Disorders - physiopathology myelin deficiency Myelin Sheath - pathology neurodegenerative disease Neurodegenerative Diseases - complications Neurodegenerative Diseases - pathology Neurological disorders rat Rats Rats, Sprague-Dawley Rodents |
title | Locomotor Analysis of the Taiep Rat |
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