New insights into the structure-function relationships and therapeutic applications of cholera-like enterotoxins

Cholera toxin and E. coli heat-labile enterotoxin are structurally homologous proteins comprised of an enzymatically active A-subunit and five B-subunits that bind with high affinity to GM1-ganglioside receptors found on the surface of mammalian cells. The B-subunits have long been thought of simply...

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Veröffentlicht in:	International journal of medical microbiology 2001, Vol.291 (6), p.531-535
Hauptverfasser:	Hirst, Timothy R., Fraser, Sylvia, Soriani, Marco, Aman, A. Tholib, de Haan, Lolke, Hearn, Arron, Merritt, Ethan
Format:	Artikel
Sprache:	eng
Schlagworte:	Cholera toxin delivery of peptides E. coli heat-labile enterotoxin signalling trafficking
Online-Zugang:	Volltext
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