The Dynamic Alterations of H2AX Complex during DNA Repair Detected by a Proteomic Approach Reveal the Critical Roles of Ca2+/Calmodulin in the Ionizing Radiation-induced Cell Cycle Arrest

By using DNA nuclease digestion and a quantitative “dual tagging” proteomic approach that integrated mass spectrometry, stable isotope labeling, and affinity purification, we studied the histone H2AX-associating protein complex in chromatin in mammalian cells in response to ionizing radiation (I...

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Veröffentlicht in:	Molecular & cellular proteomics 2006-06, Vol.5 (6), p.1033-1044
Hauptverfasser:	Du, Yu-Chun, Gu, Sheng, Zhou, Jianhong, Wang, Tianyi, Cai, Hong, MacInnes, Mark A., Bradbury, E. Morton, Chen, Xian
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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