NF-κB Inhibits Sodium Transport via Down-regulation of SGK1 in Renal Collecting Duct Principal Cells

Tubulointerstitial inflammation is a common feature of renal diseases. We have investigated the relationship between inflammation and Na+ transport in the collecting duct (CD) using the mCCDcl1 and mpkCDDcl4 principal cell models. Lipopolysaccharide (LPS) decreased basal and aldosterone-stimulated a...

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Veröffentlicht in:	The Journal of biological chemistry 2008-09, Vol.283 (37), p.25671-25681
Hauptverfasser:	de Seigneux, Sophie, Leroy, Valérie, Ghzili, Hafida, Rousselot, Martine, Nielsen, Søren, Rossier, Bernard C., Martin, Pierre-Yves, Féraille, Eric
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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