Critical Contribution of Aromatic Rings to Specific Recognition of Polyether Rings

To address how proteins recognize polyether toxin compounds, we focused on the interaction between the ABC ring compound of ciguatoxin 3C and its specific antibody, 1C49. Surface plasmon resonance analyses indicated that Escherichia coli-expressed variable domain fragments (Fv) of 1C49 had the high...

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Veröffentlicht in:The Journal of biological chemistry 2008-05, Vol.283 (18), p.12259-12266
Hauptverfasser: Tsumoto, Kouhei, Yokota, Akiko, Tanaka, Yoshikazu, Ui, Mihoko, Tsumuraya, Takeshi, Fujii, Ikuo, Kumagai, Izumi, Nagumo, Yoko, Oguri, Hiroki, Inoue, Masayuki, Hirama, Masahiro
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Sprache:eng
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