Cellular Distribution, Post-translational Modification, and Tumorigenic Potential of Human Group III Secreted Phospholipase A2

Human group III secreted phospholipase A2 (sPLA2-III) consists of a central group III sPLA2 domain flanked by unique N- and C-terminal domains. We found that the sPLA2 domain alone was sufficient for its catalytic activity and for its prostaglandin E2 (PGE2)-generating functions in various cell type...

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Veröffentlicht in:The Journal of biological chemistry 2005-07, Vol.280 (26), p.24987-24998
Hauptverfasser: Murakami, Makoto, Masuda, Seiko, Shimbara, Satoko, Ishikawa, Yukio, Ishii, Toshiharu, Kudo, Ichiro
Format: Artikel
Sprache:eng
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