Sterol-responsive Element-binding Protein (SREBP) 2 Down-regulates ATP-binding Cassette Transporter A1 in Vascular Endothelial Cells

ATP-binding cassette transporter A1 (ABCA1) is a pivotal regulator of cholesterol efflux from cells to apolipoproteins, whereas sterol-responsive element-binding protein 2 (SREBP2) is the key protein regulating cholesterol synthesis and uptake. We investigated the regulation of ABCA1 by SREBP2 in va...

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Veröffentlicht in:The Journal of biological chemistry 2004-11, Vol.279 (47), p.48801-48807
Hauptverfasser: Zeng, Lingfang, Liao, Hailing, Liu, Yi, Lee, Tzong-Shyuan, Zhu, Minjia, Wang, Xian, Stemerman, Michael B., Zhu, Yi, Shyy, John Y.-J.
Format: Artikel
Sprache:eng
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